5.12 Echocardiographic Study with Tissue Velocity and Strain Imaging Evaluation on the Effects of Exercise Training on S
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Heart 5.12 Echocardiographic Study with Tissue Velocity and Strain Imaging Evaluation on the Effects of Exercise Training on Systo-Diastolic Ventricular Dysfunction In Patients With Hypertension M. Leggio (1), L. Sgorbini (2), G. Cruciani (1), G.R. Cristinziani (1), A. Mazza (3), M.G. Bendini (3), F. Leggio (2), A.P. Jesi (1) (1)A.C.O. San Filippo Neri, Roma; (2)Ospedale I.N.R.C.A. - I.R.C.C.S., Roma; (3)Ospedale Santa Maria della Stella, Orvieto, Italy Introduction. New echocardiographic techniques, such as tissue Doppler imaging (TDI) and strain imaging (SI) have improved the assessment of systo-diastolic ventricular function in terms of accuracy and precision. A very interesting issue should be to examine, by means of these innovative echocardiographic tools, if exercise training could be able to improve the pattern of early mild systo-diastolic dysfunction frequently characterizing hypertensive patients. Aim. To evaluate left ventricular morphologic and functional parameters with traditional echocardiography, TDI and SI in patients with hypertension at baseline and at the end of a specific exercise training program for primary prevention of cardiovascular disease (CVD). Methods. We evaluated 84 patients, mean age 58±10 years, 49 males, with treated hypertension who underwent a specific exercise training program, consisting in three exercise training sessions a week with endurance protocol on a treadmill or a cycle ergometer. Systolic and diastolic blood pressure, heart rate and antihypertensive drug therapy were stable in the last 3 months; apart from familiar history of CVD, no other risk factors nor systemic diseases were represented in the study population. All patients were evaluated at baseline and at the end of the training program with traditional echocardiography, TDI and SI: for all patients, mean values of peak systolic, early diastolic and late diastolic velocities of the septal, lateral, inferior and anterior region of the mitral annulus were calculated; peak strain values of basal interventricular septum were also obtained. Results. Main characteristics of the study population, antihypertensive drug therapy and traditional echocardiographic parameters showed no significant variations from baseline to the end of the program. About TDI parameters, mean values of peak systolic velocities were significantly increased (6.1 4±1.5 cm/s baseline, 7.13 ±1.8 cm/s end, p
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