5.16 Left Ventricular Geometry In Chronic Kidney Disease
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Heart 5.16 Left Ventricular Geometry In Chronic Kidney Disease E. Nardi (1), A. Palermo (1), G. Mule` (1), P. Cusimano (1), S. Cottone (1), A. Re (1), T. Bellavia (1), G. Cerasola (1) (1)Dipartimento di Medicina Interna, Malattie Cardiovascolari e ` di Palermo, Palermo, Italy Nefrourologiche, Universita Introduction. Left ventricular hypertrophy (LVH) is highly prevalent among patients with chronic kidney disease (CKD). In this study we evaluated the prevalence of LVH, LV geometry, and the prevalence of inappropriate left ventricular mass (LVM) in a group of hypertensive patients with stage 2-5 CKD. Methods. 293 hypertensive patients with CKD (M/F: 175/118; age: 59.3±13.7 years) underwent an echocardiographic exam (Acuson Sequoia 512). Patients with stage 1 CKD, on dialysis treatment, with obesity, coronary artery disease, and valvular diseases had been excluded. Results. The prevalence of LVH and of inappropriate LVM were 47,1% and 52,9%, respectively, and both prevalence were progressively higher from stage 2 to stage 5 CKD(p=0.00 01 for both); we also observed a progressive increase of both LV wall thicknesses and LV diameters (p125 g/m2 in men and >110 g/m2 in women, RWT>0,45, and end-diastolic diameter indexed by body surface area (DD/m2) >3,2 in men and >3,1 in women). The prevalence of mixed LVH was progressively higher from stage 2 to 5 (p=0.0001). Multiple regression analysis showed that the association between LVM adrenal function (beta: -0.287; p
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