5.21 Blood Pressure Levels, Left Ventricular Mass and Function are correlated with Left Atrial Volume in Mild to Moderat
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Heart 5.21 Blood Pressure Levels, Left Ventricular Mass and Function are correlated with Left Atrial Volume in Mild to Moderate Hypertensive Patients A. Milan (1), S. Delcolle (1), M. Caserta (1), D. Naso (1), C. Magnino (1), E. Puglisi (1), F. Tosello (1), A. Viola (1), F. Veglio (1) (1)A.O.U San Giovanni Battista, Molinette, Torino, Italy Introduction. Arterial hypertension is associated with an increased risk of atrial fibrillation (AF), and leads to a pronounced increase in morbidity and mortality. Left atrial volume (LAV) is an important prognostic marker in older populations. Aim. To identify the clinical and echocardiographic determinants of LAV in middle aged (less than 70 years old) essential hypertensive (EH) patients. Methods. We evaluated cardiac structure and function in 458 subjects, 394 treated and untreated mild to moderate essential hypertensive patients (mean±standard deviation (SD) age 48.4±11.1 years) with no associated clinical condition and 64 normotensive control subjects (age 45.7±12.8; p=0.12). A multivariate analysis was performed to calculate the relative weight of each of the considered variables able to predict LAV. Results. LAV index was significantly increased in EH vs the control group and was significantly dependent on blood pressure levels (SBP and DBP, p
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