9.15 Hypertension and Metabolic Syndrome after Liver Transplantations
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High Blood Press Cardiovasc Prev 2008; 15 (3): 171-215 1120-9879/08/0003-0171/$48.00/0 © 2008 Adis Data Information BV. All rights reserved.
Metabolic Aspects and Mechanisms 9.15 Hypertension and Metabolic Syndrome after Liver Transplantations Leoni (1), B. Stagni (1), E. Silvagni (1), C. Caprara (1), S. Flori (1), L. Bolondi (1) (1)Azienda Ospedaliera Sant Orsola Malpighi, Bologna, Italy Aim. To investigate the prevalence of metabolic syndrome after orthotropic liver transplantation (OLT) and separately analyse the role of metabolic features included in metabolic syndrome definition: arterial hypertension, diabetes, serum triglyceride and high density lipoprotein (HDL) level, body mass index (BMI). Secondary aim was to evaluate possible correlation with immunosuppressive agents. Methods. We retrospectively reviewed charts of 55 OLT recipients (44 males, 11 females). Indications for OLT were hepatocellular carcinoma (28/55), virus-related cirrhosis (21/55), alcoholrelated cirrhosis (2/55), primary biliary cirrhosis (1/55) and cryptogenic cirrhosis(3/55). Mean age of patients was 50 years (range 22-66). Mean follow-up was 72.7 months (range 12-144). According to guidelines, metabolic syndrome was defined the presence of at least 3 of following criteria: blood pressure >130/85mmHg, fasting plasma glucose >110mg/dl, serum triglyceride level >150 mg/dl, HDL
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