A Brief History of Blood and Lymphatic Vessels

This book provides a comprehensive account of vascular biology and pathology and its significance for health and disease. It systematically and chronologically explains how we came to our current understanding of the vasculature and it´s  function to

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A Brief History of Blood and Lymphatic Vessels

A Brief History of Blood and Lymphatic Vessels

Andreas Bikfalvi

A Brief History of Blood and Lymphatic Vessels

Andreas Bikfalvi Angiogenesis and Tumor Microenvironment Laboratory University of Bordeaux and National Institute of Health and Medical Research Pessac, France

The work was first published in 2016 by EDP Sciences with the following title: Une brève histoire de vaisseau sanguin et lymphatique ISBN 978-3-319-74375-2 ISBN 978-3-319-74376-9 https://doi.org/10.1007/978-3-319-74376-9

(eBook)

Library of Congress Control Number: 2018932419 # Springer International Publishing AG, part of Springer Nature 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by the registered company Springer International Publishing AG part of Springer Nature. The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Foreword

The vascular tree irrigates all tissues throughout the body, provides oxygenation and nutrient supply, and eliminates waste products. It is a system of considerable size and of paramount importance because, without a vascular connection, tissue dies. In humans, more than 80 diseases are linked to dysfunction of the vascular system. Understanding how the vascular tree is formed is therefore a major issue in medical research. This book provides a historical view of important discoveries in angiogenesis research, information about current studies, and a discussion of still unresolved issues. It also contains a section of more conceptual and philosophical aspects related to the field. It is important that a recognized scientist actively working in this field write a synthesis on this topic. In this book, Andreas Bikfalvi faced a triple challenge: To write a book that is interesting and readable for both the specialist and the gen