A comparative study of clinical effect of total knee arthroplasty in the treatment of primary osteoarthritis and osteoar
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ORIGINAL PAPER
A comparative study of clinical effect of total knee arthroplasty in the treatment of primary osteoarthritis and osteoarthritis of Kashin-Beck disease Hui-Min Liu 1 & Ya-Fei Wang 1 & Jian-Min Wu 1 & Bo-Yuan Li 2 & Feng Dong 1 & Dai-Feng Lu 1 & Hong-Xi Li 1 & Zhi-Tao Zhang 1 & Cong Yu 1 & Yong-Yun Lian 1 Received: 15 December 2019 / Accepted: 18 March 2020 # SICOT aisbl 2020
Abstract Objective To evaluate the clinical efficacy of total knee arthroplasty (TKA) in the treatment of primary osteoarthritis (OA) and osteoarthritis of Kashin-Beck disease (KBD). Methods This study enrolled 77 KBD patients (77 knees, KBD-TKA) and 75 OA patients (75 knees, OA-TKA) who underwent TKA from September 2008 to June 2018. Clinical assessments for each patient were performed pre-operatively and last followup. The efficacy measures included the visual analogue scale (VAS) pain score, range of motion (ROM), Hospital for Special Surgery (HSS) score, and short form 36 Health Survey (SF-36) as well as related influencing factors between the two groups. Results All patients were followed up; the follow-up time of KBD-TKA was 14–132 months, with an average of 72.68 ± 37.55 months; OA-TKA was 15–120 months, with an average of 49.2 ± 28.91 months. There was no difference in preoperative VAS score (7.29 vs. 7.24) and SF-36 (PCS) score (4.87 vs. 5.49) between KBD-TKA and OA-TKA (P > 0.05), while compared with OA, KBD-TKA had significantly worse pre-operative ROM (75.48° vs. 82.87°), HSS score (36.40 vs. 41.84), and SF-36 (MCS) score (26.28 vs. 28.73) (P < 0.05). At the final follow-up, there was no significant difference in VAS score (1.13 vs. 1.16), ROM (105.79 vs. 105.79), and HSS score (92.06 vs. 92.25) between KBD-TKA and OA-TKA (P > 0.05), while compared with OA, KBD-TKA had significantly worse SF-36 (PCS) score (36.90 vs. 42.00) and SF-36 (MCS) score (55.16 vs. 59.70) (P < 0.05). In a multivariate regression, controlling for multiple potential confounders, diagnosis of KBD was associated with poor quality of life after surgery, whereas pre-operative pain was specifically associated with post-operative pain. However, preoperative gender, age, BMI, and the angles of knee prosthesis (before and after surgery) were not associated with postoperative outcome.
Hui-Min Liu and Ya-Fei Wang are the co-first authors. * Yong-Yun Lian [email protected]
Hong-Xi Li [email protected]
Hui-Min Liu [email protected]
Zhi-Tao Zhang [email protected]
Ya-Fei Wang [email protected]
Cong Yu [email protected]
Jian-Min Wu [email protected] Bo-Yuan Li [email protected] Feng Dong [email protected] Dai-Feng Lu [email protected]
1
Department of Orthopaedic Surgery, The Fourth Affiliated Hospital Of Harbin Medical University, No. 37, Yiyuan street, Nangang District, Harbin City, Heilongjiang Province, China
2
Department of Orthopaedic Surgery, Heilongjiang Provincial Hospital, No 82, Zhongshan road, Harbin city, Heilongjiang province, China
International Orthopaedics (SICOT)
Conclusion Patients with KBD undergoing primary TKA have exce
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