Abstracts from hydrocephalus 2018: the tenth meeting of the International Society for Hydrocephalus and Cerebrospinal Fl
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MEETING ABSTRACTS
Fluids and Barriers of the CNS Open Access
Abstracts from hydrocephalus 2018: the tenth meeting of the International Society for Hydrocephalus and Cerebrospinal Fluid Disorders Bologna, Italy. 19–22 October 2018 Published: 24 December 2018 I1 Introduction Giorgio Palandri Hydrocephalus 2018 President Consultant, Department of Neurosurgery, IRCCS Institute of Neurological Sciences of Bologna, Bellaria Hospital, Bologna, Italy Correspondence: Giorgio Palandri: [email protected] Fluids and Barriers of the CNS 2018, 15(Suppl 2):I1 It has been a great privilege and honour for me and my team to host the 10th meeting of Hydrocephalus Society (International Society for Hydrocephalus and CSF Disorders) in the historic city of Bologna, Italy. This annual meeting was dedicated to research into hydrocephalus and related disorders and attracted over 300 delegates from 32 different countries. Hydrocephalus 2018 presented a vital opportunity for clinicians and scientists to stay current on advances in the assessment, diagnosis and treatment of hydrocephalus. The delegates included many different professionals, who in very different ways and fields, deal every day with patients suffering from hydrocephalus: for example, engineers, physicists, nurses, radiologists, neurologists, neuroscientists, neurosurgeons, geriatricians, anaesthetists and neuropsychologists. Delegates heard keynote lectures by the world’s experts on many topics including pediatric hydrocephalus, experimental hydrocephalus, normal pressure hydrocephalus, diagnosis, shunt technology, pathophysiology and brain imaging. We also had a great social program starting with a Welcome Reception at the Lamborghini Museum, followed on successive evenings by an Italian evening and a Gala dinner. Altogether, we enjoyed a very successful and exciting meeting here in Bologna. O1 CSF amyloid Β‑related and neurofilament light proteins in the differential diagnosis of normal pressure hydrocephalus Samir Abu‑Rumeileh1, Giulia Giannini1, Luca Albini‑Riccioli2, Barbara Polischi2, David Milletti2, Federico Oppi2, Paolo Mantovani2, Giorgio Palandri2, Pietro Cortelli1,2, Sabina Cevoli2, Piero Parchi2,3 1 Department of Biomedical and NeuroMotor Sciences (DIBINEM), University of Bologna, Italy; 2IRCCS Institute of Neurological Sciences of Bologna, Bellaria Hospital, Italy; 3Department of Diagnostic Experimental and Specialty Medicine (DIMES), University of Bologna, Italy Correspondence: Piero Parchi Fluids and Barriers of the CNS 2018, 15(Suppl 2):O1 Introduction: The diagnosis of normal pressure hydrocephalus (NPH) can be quite challenging given the phenotypic overlap with other cognitive disorders. Moreover, knowledge about the pathophysiological mechanism leading to neurological dysfunction in NPH is limited.
Cerebrospinal fluid (CSF) biomarkers have been investigated to these aims, but the results appear discordant among studies. Methods: We measured CSF amyloid β (Aβ)42 and Aβ40, neurofilament light chain protein (NfL), total(t)-tau and phosphorylated(
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