Acute Lymphoblastic Leukemia (ALL) in Children and Adolescents
Child and adolescent patients who are diagnosed with acute lymphoblastic leukemia (ALL), both of B-cell or T-cell phenotype, have excellent outcomes when treated with various multiagent chemotherapy regimens. The presentation and early medical management
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Stefan H. Faderl Hagop M. Kantarjian Elihu Estey Editors
Acute Leukemias Second Edition
Hematologic Malignancies Series Editor Martin Dreyling München, Germany
This series of professional books provides in-depth information on all aspects of the diagnosis and treatment of different hematologic cancers, including clinical evaluation, imaging diagnosis, staging, current treatment strategies, novel targeted approaches, and evaluation of treatment response. Readers will also find coverage of methodological and research issues and factors that influence treatment outcome. Each volume is designed to serve both as a quick reference and as a comprehensive source of knowledge that will be invaluable in improving management of the malignancy under consideration. The volume editors and authors have been selected for their international reputations and acknowledged expertise. The series will appeal to hematologists and oncologists in hospitals or private practices, residents, and others with an interest in the field. More information about this series at http://www.springer.com/series/5416
Stefan H. Faderl Hagop M. Kantarjian • Elihu Estey Editors
Acute Leukemias Second Edition
Editors Stefan H. Faderl Reno NV USA Elihu Estey Clinical Research Division Fred Hutch Seattle, WA USA
Hagop M. Kantarjian Department of Leukemia MD Anderson Cancer Center, University of Texas Houston, TX USA
ISSN 2197-9766 ISSN 2197-9774 (electronic) Hematologic Malignancies ISBN 978-3-030-53632-9 ISBN 978-3-030-53633-6 (eBook) https://doi.org/10.1007/978-3-030-53633-6 © Springer Nature Switzerland AG 2021 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Contents
Part I Acute Myeloid Leukemia 1 Acute
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