Adenoid cystic carcinoma of the lacrimal gland metastasising to the liver: report of a case
- PDF / 1,272,344 Bytes
- 4 Pages / 610 x 792 pts Page_size
- 7 Downloads / 162 Views
Open Access
Case report
Adenoid cystic carcinoma of the lacrimal gland metastasising to the liver: report of a case Bashar A Zeidan1, Mohammed Abu Hilal1, Mohammed Al-Gholmy1, Hanan El-Mahallawi2, Neil W Pearce*1 and John N Primrose1 Address: 1Hepato Pancreatico Biliary Surgery Unit – Southampton General Hospital, Southampton, SO16 6YD, UK and 2Department of Histopathology – Southampton General Hospital, Southampton, SO16 6YD, UK Email: Bashar A Zeidan - [email protected]; Mohammed Abu Hilal - [email protected]; Mohammed AlGholmy - [email protected]; Hanan El-Mahallawi - [email protected]; Neil W Pearce* - [email protected]; John N Primrose - [email protected] * Corresponding author
Published: 20 September 2006 World Journal of Surgical Oncology 2006, 4:66
doi:10.1186/1477-7819-4-66
Received: 02 April 2006 Accepted: 20 September 2006
This article is available from: http://www.wjso.com/content/4/1/66 © 2006 Zeidan et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract Background: Adenoid Cystic Carcinoma of the lacrimal gland is a rare tumour. Their aggressive behaviour, with a high-risk of local recurrence, and late distant spread of the tumour even after aggressive management has been reported. Metastasis to the liver is rare and when it occurs, it is usually part of widespread metastasis, and therefore surgical treatment is seldom considered. Case presentation: We report a rare case of an isolated liver metastasis from a lacrimal gland adenoid cystic carcinoma 20 years after resection of the primary tumour. The patient presented with right upper quadrant pain radiating to the back and shortness of breath of 3 months duration. No local recurrence was detected during a 15 year follow-up with computerized tomography (CT) of the head. Abdominal CT scan demonstrated a solitary liver tumour with no other primary source, and the bone scan was normal. The patient was treated with an extended right hemihepatectomy. The histology revealed a predominantly cribriform tumour with focal areas of basaloid type metastatic lacrimal gland adenoid cystic carcinoma. Conclusion: This case illustrates the unpredictable behaviour of adenoid cystic carcinoma and the need for a life long follow up for these patients after treatment. The possibility of surgical resection for liver metastasis from adenoid cystic carcinoma should always be considered.
Background Adenoid cystic carcinomas (ACC) of the lacrimal gland are rare malignant tumours accounting for 1.6% of all orbital tumours [1-3]. Despite their rarity they are the second most frequent epithelial neoplasms occurring in the lacrimal gland after pleomorphic adenomas [4]. They are slow growing tumours, which tend to spread to adjacent structures and occasionally metastasise via hae-
matogeno
Data Loading...
