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Status epilepticus: case report An 8-year-old boy developed status epilepticus during treatment with amoxicillin and cefdinir for paediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS). The boy, who had a history of motor tics, attention deficit hyperactivity disorder (ADHD) and a recent seizure, was referred to the Emergency Department (ED) in status epilepticus on 22 April 2020. His mother reported that he woke up early in the morning of presentation with complaints of abdominal pain and nausea. He noted that his head was turned to the left and his eyes were looking upward. He had experienced 3 episodes of vomiting, which were non-bloody and non-bilious while his head was still turned left. While being transferred to the ED, he was reportedly in and out of consciousness. Results of a routine EEG performed at a neurology visit 2.5 weeks before this presentation were abnormal, with intermittent waves and spikes. Neurology had been monitoring the boy because of recent complaints of motor tics and ADHD. The diagnosis of possible PANDAS was considered, and he was treated with a 10-day course of amoxicillin. His mother was instructed to administer only amoxicillin for the first 5 days and then to administer amoxicillin along with cefdinir [routes and dosages not stated] for the following 5 days, both of which could lower the seizure threshold. An MRI, which was scheduled on 12 May 2020 was postponed because of the COVID pandaemic. In the ED, he was experiencing a left-sided focal seizure with blinking of the left eye and rhythmic movement of the left arm for 30 minutes. The boy was administered lorazepam with levetiracetam, and the seizure seemed to subside. He started having agonal breathing (respiratory distress) and desaturations and underwent an emergent intubation. The chest x-ray and the need for intubation prompted a COVID-19 test. The chest X-ray showed bilateral infiltrates, for which ceftriaxone was administered. The result of reverse transcription-polymerase chain reaction testing (RT-PCR) for SARS-CoV-2 was found to be positive. As a result of recommendations and clinical experience at that time, a 5-day course of off-label oral hydroxychloroquine 200mg was started. Soon after arrival at the Pediatric PICU, he was extubated and was stable on room air without any additional seizure activity. Methylprednisolone and magnesium were administered for respiratory support, and cholecalciferol and ascorbic acid were administered for additional nutritional support. During hospitalisation, enoxaparin sodium [enoxaparin] was given. During the entire hospital stay, his temperature remained normal. Laboratory results on day 2 revealed an increase in absolute neutrophil count and a decrease in absolute lymphocyte count (lymphopenia), with a neutrophil-to-lymphocyte ratio of 8.92. The 24-hour ECG result was abnormal, suggestive of diffuse cerebral dysfunction of non-specific aetiology. He remained clinically stable and was discharged home to quarantine and to complete a cour