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Anaphylaxis: 3 case reports In a review of 275 cases of childhood anaphylaxis in the United states in year 2016, 3 male infants aged 4–10 months were described, who developed anaphylaxis (including skin, GI tract or respiratory tract) to nystatin, ceftriaxone or amoxicillin [not all routes stated, indications, time to reaction onsets and outcomes not stated]. Patient 1: The 4-month-old male infant, who received oral nystatin developed anaphylaxis. The body systems involved in the anaphylaxis were skin and respiratory system. Subsequently, he was treated with 2 doses of racemic epinephrine, single dose of epinephrine with diphenhydramine, ranitidine and dexamethasone. Patient 4: The 6-month-old male infant, who received ceftriaxone developed anaphylaxis. The body systems involved in the anaphylaxis were skin and GI system. Subsequently, he was treated epinephrine and albuterol. Patient 9: The 10-month-old male infant, who received amoxicillin developed anaphylaxis. The body systems involved in the anaphylaxis were skin and respiratory system. Subsequently, he was treated with epinephrine, albuterol, bolus sodium chloride [saline], diphenhydramine and ranitidine. Anvari S, et al. Insights from 275 cases of childhood anaphylaxis in the United States. The Journal of Allergy and Clinical Immunology in Practice 7: 1696-1699.e2, No. 5, 803500298 May-Jun 2019. Available from: URL: http://doi.org/10.1016/j.jaip.2018.12.013

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Reactions 12 Sep 2020 No. 1821