Anal Cancer A Comprehensive Guide
This book is a comprehensive overview of the epidemiology, pathogenesis, and treatment options available for anal cancer. Anal cancer is a relatively rare disease, but one increasing in incidence. Strides have been made in developing treatment paradigms t
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Anal Cancer
Jeffrey Meyer • Lisa Kachnic Editors
Anal Cancer A Comprehensive Guide
Editors Jeffrey Meyer, MD, MS Department of Radiation Oncology Johns Hopkins School of Medicine Baltimore, MD, USA
Lisa Kachnic, MD, FASTRO Department of Radiation Oncology Vanderbilt University School of Medicine Nashville, TN, USA
ISBN 978-3-030-20252-1 ISBN 978-3-030-20253-8 (eBook) https://doi.org/10.1007/978-3-030-20253-8 © Springer Nature Switzerland AG 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
I dedicate this book to the many patients that I have had the privilege to care for during my career. They have all shaped me into the physician and person I am today, and I hope that I have positively touched their lives in return. Lisa Kachnic
Preface
A multidisciplinary team approach is paramount to the management of anal cancer; however, due to its low incidence as compared to other solid cancers, there are limited comprehensive published treatment guidelines. This need has become increasingly important over the past several years when we have seen advances in the prevention, detection, radiation delivery, and systemic approaches including immunotherapy. As a result, it is currently very difficult for a clinician (either in training or in practice) to gain experience and expertise in the multidisciplinary management of this rare cancer. Anal Cancer: A Comprehensive Guide was created for the purpose of centralizing the knowledge and experience of experts across a variety of disciplines. The authors provide an overview of the principles of disease pathogenesis, anatomy, epidemiology, and staging, in addition to detailed established and cutting- edge clinical approaches for the tr
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