Antibiotics in the Tropics Antibacterial Therapy with Limited Resour
International textbooks on infectious diseases and antibacterial chemotherapy are usually written for readers in North America and Europe. In many ways, they are not appropriate for the prob lems encountered in developing countries. This book, in contras
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Antibiotics in the Tropics Antibacterial Therapy with Limited Resources
With 16 Figures and 132 Tables
Springer-Verlag Berlin Heidelberg New York London Paris Tokyo
Dr. med. Sabine Enenkel of Pediatrics
Departme~t
Professor Dr. Wolfgang Stille Department of Internal Medicine University Hospital, Johann Wolfgang Goethe-UniversiUit, Theodor-Stern-Kai 7, 6000 Frankfurt/Main 70, FRG
ISBN-13: 978-3-540-18683-0 001: 10.1007/978-3-642-73276-8
e-ISBN-13: 978-3-642-73276-8
Library of Congress Cataloging-in-Publication Data. Enenkel, S. (Sabine), 1957-. Antibiotics in the tropics. Includes bibliographies and index. 1. Bacterial diseases Developing countries - Chemotherapy. 2. Antibiotics - Developing countries. 3. Tropical medicine. I. Stille, W. (Wolfgang) II. Title. [DNLM: 1. Antibiotics - therapeutic use. 2. Bacterial Infections - drug therapy. 3. Tropical Medicine. QV 350 E56a] RC115.E54 1988 616.9'2061 87-37652 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in other ways, and storage in data banks. Duplication of this publication or parts thereof is only permitted under the provisions of the German Copyright Law of September 9, 1965, in its version of June 24, 1985, and a copyright fee must always be paid. Violations fall under the prosecution act of the Germann Copyright Law. © Springer-Verlag Berlin Heidelberg 1988 The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product Liability: The publisher can give no guarantee for information about drug dosage and application thereof contained in the book. In every individual case the respective user must check its accuracy by consulting other pharmaceutical literature. 2119/3140-543210
Preface
International textbooks on infectious diseases and antibacterial chemotherapy are usually written for readers in North America and Europe. In many ways, they are not appropriate for the problems encountered in developing countries. This book, in contrast, intends to define the rules of antibacterial chemotherapy practised under conditions of limited resources. It is meant for everyone concerned with the use of antibiotics in developing countries, including doctors, medical assistants, pharmacists, officials in health mioisteries, and medical students. Throughout the book, treatment recommendations are made for antibiotics from the WHO list of essential drugs. 1 For example, emphasis has therefore been put upon chloramphenicol as a stable, unexpensive and widely available oral agent suitable for the treatment of severe bacterial infections like septicemia and meningitis. So-called "international chemotherapy" with modem cephalosporins and acylaminopenicillins has been outlined for comparison.
