Antiseptic Stewardship Biocide Resistance and Clinical Implications

VVarious antiseptic agents, such as chlorhexidine, are used for different applications, e.g. in healthcare, veterinary medicine, animal production and household products, including cosmetics. However, not all antiseptic agents provide significant health b

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Antiseptic Stewardship Biocide Resistance and Clinical Implications

Antiseptic Stewardship

Günter Kampf

Antiseptic Stewardship Biocide Resistance and Clinical Implications

123

Günter Kampf Institute of Hygiene and Environmental Medicine University of Greifswald Greifswald, Germany

ISBN 978-3-319-98784-2 ISBN 978-3-319-98785-9 https://doi.org/10.1007/978-3-319-98785-9

(eBook)

Library of Congress Control Number: 2018950922 © Springer Nature Switzerland AG 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Foreword

Biocides (disinfectants, antiseptics, preservatives) usage has increased worldwide notably for applications that do not necessarily require the application of biocides, particularly in the home environment. The amount of biocides used in Europe is difficult to quantify as the number of products containing a biocide and biocide applications have increased dramatically in the last 10 years. It is thus logical to assume that microbial exposure to biocides has also increased. Parallel, but not separate, from the increase in biocidal products commercially available is the rise in antimicrobial resistance (AMR) in bacteria, which results primarily from the overuse and misuse of chemotherapeutic antibiotics for human and veterinary medicine, but also for industrial processes such as fermentation. Recent calculations from Lord O’Neil’s AMR report to the British government predict human deaths caused by untreatable AMR to reach 10 million worldwide by 2050, well above other diseases including cancer. Biocidal products have a role to play in reducing AMR notably on hard and porous surfaces, with disinfection and antisepsis, and in products through preservation. The increase in biocidal