Applied Physiology in Intensive Care Medicine 2 Physiological Review

The two previous editions of Applied Physiology in Intensive Care Medicine proved extremely successful, and the book has now been revised and split into two volumes to enhance ease of use. In this second volume some of the most renowned experts in the fie

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pplied Physiology in Intensive Care Medicine 2

M. R. Pinsky · L. Brochard · J. Mancebo M. Antonelli (Eds.)

Applied Physiology in Intensive Care Medicine 2 Physiological Reviews and Editorials Third Edition

Editors MICHAEL R. PINSKY, MD Dept. of Critical Care Medicine University of Pittsburgh Medical Center Scaife Hall 606 3550 Terrace Street Pittsburgh, PA 15261 USA

LAURENT BROCHARD, MD Dept. Intensive Care Medicine Hôpital Henri Mondor 51 av. Maréchal Lattre de Tassigny 94010 Créteil CX France

JORDI MANCEBO, MD Dept. Intensive Care Medicine Hospital de Sant Pau Avda. S. Antonio M. Claret 167 08025 Barcelona Spain

MASSIMO ANTONELLI General Intensive Care Unit Università Cattolica des Sacro Cuore Largo A. Gemelli 8 00168 Rome Italy

„ The articles in this book appeared in the journal “ Intensive Care Medicine between 2002 and 2011.

ISBN 978-3-642-28232-4 e-ISBN 978-3-642-28233-1 DOI 10.1007/978-3-642-28233-1 Springer Heidelberg New York Dordrecht London Library of Congress Control Number: 2012933785 ¤ Springer-Verlag Berlin Heidelberg 2006, 2009, 2012 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

Preface

Perhaps no field of medicine witnesses such dynamic change in practice over similar time intervals as the practice of intensive care medicine. Thus, the