Aromaticity in Heterocyclic Compounds

Aromaticity is a notion that appeared in the mid-nineteenth century to differentiate between unsaturated hydrocarbons and formally unsaturated benzene [1–3]. At the end of the nineteenth century it seemed that cyclicity was a necessary condition for diffe

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Topics in Heterocyclic Chemistry Series Editor: R.R. Gupta

Editorial Board: D. Enders · S.V. Ley · G. Mehta · K.C. Nicolaou R. Noyori · L.E. Overman · A. Padwa

Topics in Heterocyclic Chemistry Series Editor: R. R. Gupta Recently Published and Forthcoming Volumes

Aromaticity in Heterocyclic Compounds Volume Editors: T. Krygowski, M. Cyrański Volume 19, 2009

Bioactive Heterocycles III Volume Editor: M.T.H. Khan Volume 9, 2007

Heterocyclic Supramolecules I Volume Editor: K. Matsumoto Volume 17, 2008

Bioactive Heterocycles II Volume Editor: S. Eguchi Volume 8, 2007

Bioactive Heterocycles VI Flavonoids and Anthocyanins in Plants, and Latest Bioactive Heterocycles I Volume Editor: N. Motohashi Volume 15, 2008

Heterocycles from Carbohydrate Precursors Volume Editor: E.S.H. ElAshry Volume 7, 2007

Heterocyclic Polymethine Dyes Synthesis, Properties and Applications Volume Editor: L. Strekowski Volume 14, 2008 Synthesis of Heterocycles via Cycloadditions II Volume Editor: A. Hassner Volume 13, 2008 Synthesis of Heterocycles via Cycloadditions I Volume Editor: A. Hassner Volume 12, 2008 Bioactive Heterocycles V Volume Editor: M.T.H. Khan Volume 11, 2007 Bioactive Heterocycles IV Volume Editor: M.T.H. Khan Volume 10, 2007

Bioactive Heterocycles I Volume Editor: S. Eguchi Volume 6, 2006 Marine Natural Products Volume Editor: H. Kiyota Volume 5, 2006 QSAR and Molecular Modeling Studies in Heterocyclic Drugs II Volume Editor: S.P. Gupta Volume 4, 2006 QSAR and Molecular Modeling Studies in Heterocyclic Drugs I Volume Editor: S.P. Gupta Volume 3, 2006 Heterocyclic Antitumor Antibiotics Volume Editor: M. Lee Volume 2, 2006

Aromaticity in Heterocyclic Compounds Volume Editors: Tadeusz M. Krygowski · Michał K. Cyrański

With Contributions by M. A. R. Matos · I. Alkorta · A.T. Balaban Z. Benkö · J. Elguero · M. Giurg · T. Gracza, A. Krutošíková · L. Latos-Grażyński · Joel F. Liebman J. Młochowski · L. Nyulászi · M. Stępień

The series Topics in Heterocyclic Chemistry presents critical reviews on “Heterocyclic Compounds” withintopic-related volumes dealing withall aspects suchas synthesis, reactionmechanisms, structure complexity, properties, reactivity, stability, fundamental and theoretical studies, biology, biomedical studies, pharmacological aspects, applications in material sciences, etc. Metabolism will be also included which will provide information useful in designing pharmacologically active agents. Pathways involving destruction of heterocyclic rings will also be dealt with so that synthesis of specifically functionalized non-heterocyclic molecules can be designed. The overall scope is to cover topics dealing with most of the areas of current trends in heterocyclic chemistry which will suit to a larger heterocyclic community. As a rule contributions are specially commissioned. The editors and publishers will, however, always be pleased to receive suggestions and supplementary information. Papers are accepted for Topics in Heterocyclic Chemistry in English. In references Topics in Heterocyclic Chemistry is abbrev

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