Asparaginase
- PDF / 140,935 Bytes
- 1 Pages / 595.245 x 841.846 pts (A4) Page_size
- 80 Downloads / 131 Views
1
S
Fatal cortical venous thrombosis: case report A 21-year-old woman started chemotherapy according to the BFM-86 protocol for acute lymphoblastic leukaemia. She received three doses of asparaginase [dosage and route not stated], daunorubicin and vincristine. She reported a headache 4 days after the third dose of asparaginase. Seizures developed 3 days later, but she stabilised with antiepileptics. A brain MRI suggested cortical venous thrombosis. This diagnosis was confirmed by a magnetic resonance venogram, which showed lack of opacification of her left transverse sinus. Nadroparin calcium was administered, but her neurological status progressively deteriorated and she died 11 days later despite all efforts. Cyriac S, et al. L-asparaginase induced fatal cortical venous thrombosis in acute lymphoblastic leukemia. Indian Journal of Hematology and Blood Transfusion 26: 8-11, No. 1, Mar 2010. Available from: URL: http://dx.doi.org/10.1007/ 803038467 s12288-010-0005-7 - India
0114-9954/10/1319-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved
Reactions 18 Sep 2010 No. 1319
Data Loading...
