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Delayed intracranial haemorrhage: 5 case reports In a retrospective study involving 793 patients, who were admitted for observation after blunt head trauma at a level I trauma center in Austria between January 2012 and April 2014, 5 patients (3 men and 2 women) aged between 54–90 years were described, who developed hygroma (n=1), intracerebral haemorrhage (n=1), subdural haemorrhage (n=1) and epidural haemorrhage (n=2) during treatment with aspirin, aspirin/clopidogrel or dabigatran etexilate for blunt head trauma [dosages, routes, duration of treatments to reactions onsets and outcomes not stated]. The patients had been receiving antithrombotic therapy with aspirin [acetylsalicylic acid; 2 patients receiving for 1 year], aspirin/clopidogrel (2 patients receiving for 2 years) and dabigatran etexilate (1 patient receiving for 2 years). They presented to a trauma center following a blunt head trauma and required in-patient admission for a minimum duration of 24 hours for observation. After hospitalisation, CT scans were performed, which led to the identification of delayed intracranial hemorrhages in all the patients in the form of hygroma (1 patient), intracerebral haemorrhage (1 patient), subdural haemorrhage (1 patient) and epidural haemorrhage (2 patients). None of the patients underwent surgical intervention, and were discharged following the observation period. Author comment: "Delayed intracranial hemorrhage can occur up to several weeks after head trauma and was reported more frequently in patients with antithrombotic therapy." Antoni A, et al. Delayed intracranial hemorrhage in patients with head trauma and antithrombotic therapy. Journal of Clinical Medicine 8: 1780, No. 11, 25 Oct 2019. 803440550 Available from: URL: http://doi.org/10.3390/jcm8111780 - Austria

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Reactions 21 Dec 2019 No. 1784