Association between serum magnesium and anemia in patients with chronic kidney disease

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NEPHROLOGY - ORIGINAL PAPER

Association between serum magnesium and anemia in patients with chronic kidney disease Zeynep Biyik1 · Yasemin Coskun Yavuz1 · Lütfullah Altintepe1 Received: 7 February 2020 / Accepted: 25 May 2020 © Springer Nature B.V. 2020

Abstract Purpose  An inverse association was shown between serum magnesium levels and anemia in the general population. However, limited information is available about the association between serum magnesium level and anemia in the patient population with chronic kidney disease. We aimed to investigate the relationship between hypomagnesemia and anemia in pre-dialysis patients with chronic kidney disease stage 3–5. Methods  This cross-sectional retrospective study included 213 chronic kidney disease patients with an estimated glomerular filtration rate of 60 mL/min and below. Laboratory and demographic data of outpatients were collected in January 2018— January 2019. Patients with a magnesium level below 1.9 mg/dL were accepted as the hypomagnesemia group. Results  Serum magnesium level of 62 (29.1%) of these patients were below 1.9 mg/dL. Compared with normomagnesemic patients, hypomagnesemic patients had lower mean hemoglobin values (11.3 g/dL vs. 12.7 g/dL, P