Ataxie
- PDF / 574,774 Bytes
- 4 Pages / 595.276 x 841.89 pts (A4) Page_size
- 10 Downloads / 144 Views
Die Indikation zur PEG-Sonde sollte bei fortgeschrittener Demenz eher selten und immer im Sinne einer Einzelfallentscheidung gestellt werden. Bei Finalstadien der Demenz ist sie kontraindiziert. Allerdings bleibt zu hoffen, dass sich diese medizinisch und ethisch problematische Fragestellung in Zukunft durch eine frühere Wahrnehmung des Gewichtsverlusts und entsprechend frühzeitige nicht invasive Therapiemaßnahmen bei einigen Betroffenen vermeiden lässt. Dr. Rainer Wirth Klinik für Geriatrie, St. Marien-Hospital Borken [email protected]
Literatur: 1. Wolf-Klein GP, Silverstone FA and Levy AP. Nutritional patterns and weight change in Alzheimer patients. Int Psychogeriatr 1992; 4:103–18 2. Wolf-Klein GP and Silverstone FA. Weight loss in Alzheimer’s disease: an international review of the literature. Int Psychogeriatr 1994; 6:135–42 3. Poehlman ET and Dvorak RV. Energy expenditure, energy intake, and weight loss in Alzheimer disease. Am
J Clin Nutr 2000; 1:650–655 4. Buchman AS et al. Change in body mass index and risk of incident Alzheimer disease. Neurology 2005; 65:892–897 5. Stewart R et al. A 32-year prospective study of change in body weight and incident dementia: the Honolulu-Asia Aging Study. Arch Neurol 2005; 62:55–60 6. Barrett-Connor E et al. Weight loss precedes dementia in community-dwelling older adults. J Am Geriatr Soc 1996; 44:1147-1152 7. Johnson DK, Wilkins CH and Morris JC. Accelerat ed weight loss may precede diagnosis in Alzheimer disease. Arch Neurol 2006; 63:1312–1317 8. Grundman M. Weight loss in the elderly may be a sign of impending dementia. Arch Neurol 2005; 62:20–22 9. Grundman M et al. Low body weight in Alzheimer’s disease is associated with mesial temporal cortex atrophy. Neurology 1996; 46:1585–1591 10. Vanhanen M et al. APOE-epsilon4 is associated with weight loss in women with AD: a population-based study. Neurology 2001; 56:655–659 11. Cronin-Stubbs D et al. Weight loss in people with Alzheimer’s disease: a prospective population based analysis. Bmj 1997; 314:178–179 12. Wirth R, Bauer JM and Sieber CC. Cognitive function, body weight and body composition in geriatric patients. Z Gerontol Geriatr 2007; 40:13–20 13. Stewart JT and Gorelik AR. Involuntary weight loss associated with cholinesterase inhibitors in dementia. J Am Geriatr Soc 2006; 54:1013–1014 14. Guerin O et al. Different modes of weight loss in Alzheimer disease: a prospective study of 395 patients. Am J Clin Nutr 2005; 82:435–441 15. Gillette-Guyonnet S et al. Long-term cholinergic treatment is not associated with greater risk of weight loss during Alzheimer’s disease: data from the French REAL.FR cohort. J Nutr Health Aging 2005; 9:69–73 16. Correia, MI and DL Waitzberg. The impact of malnutrition on morbidity, mortality, length of hospital
stay and costs evaluated through a multivariate model analysis. Clin Nutr 2003; 22:235–239 17. Milne AC, Avenell A and Potter J. Meta-analysis: protein and energy supplementation in older people. Ann Intern Med 2006; 144:37–48 18. Keller HH et al. Prevention of weight lo