Bacteriophage Applications - Historical Perspective and Future Potential

This book explores key applications of phage biotechnology and reviews recent advances in phage display technologies. The applications covered were selected on the basis of their significance and representativeness in the field. The small size and en

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Jessica Nicastro Shirley Wong Zahra Khazaei Peggy Lam Jonathan Blay Roderick A. Slavcev

Bacteriophage Applications— Historical Perspective and Future Potential 123

SpringerBriefs in Biochemistry and Molecular Biology

More information about this series at http://www.springer.com/series/10196

Jessica Nicastro Shirley Wong Zahra Khazaei Peggy Lam Jonathan Blay Roderick A. Slavcev •





Bacteriophage Applications—Historical Perspective and Future Potential

123

Jessica Nicastro School of Pharmacy University of Waterloo Waterloo, ON Canada Shirley Wong School of Pharmacy University of Waterloo Waterloo, ON Canada Zahra Khazaei Western University London, ON Canada

Peggy Lam University of Waterloo Waterloo, ON Canada Jonathan Blay School of Pharmacy University of Waterloo Waterloo, ON Canada Roderick A. Slavcev School of Pharmacy University of Waterloo Waterloo, ON Canada

ISSN 2211-9353 ISSN 2211-9361 (electronic) SpringerBriefs in Biochemistry and Molecular Biology ISBN 978-3-319-45789-5 ISBN 978-3-319-45791-8 (eBook) DOI 10.1007/978-3-319-45791-8 Library of Congress Control Number: 2016949574 © The Author(s) 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Contents

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1 1 2 2 3 3 3 4 4 5 6

2 Phage for Biocontrol . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 The Importance of Using Recombinant Phage. . . . . . . . . . . . . . 3 Recombinant Phage for the Treatment of Bacterial Infections . . 3.1 Escherichia coli (E. coli) . . . . . . . . . . . . . . . . . . . . . . . . . 3.2 Staphylococcus aureus (S. aureus) . . . . .