Best Practices in Processing and Storage for Hematopoietic Cell Transplantation

This concise book examines clinically relevant issues relating to the ways in which bone marrow, cord blood and apheresis products, are processed and stored for the purpose of Hematopoietic Cell Transplantation and Cell Therapy. The twin aims are to offer

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Joseph Schwartz Beth H. Shaz Editors

Best Practices in Processing and Storage for Hematopoietic Cell Transplantation

Advances and Controversies in Hematopoietic Transplantation and Cell Therapy Series Editors Syed A. Abutalib••• Deerfield, Illinois, USA James O. Armitage•• Omaha, Nebraska, USA

Each volume will focus on different aspects of blood and marrow transplantation or cellular therapy and presents up-to-date data and concepts as well as controversial aspects. More information about this series at http://www.springer.com/series/13907

Joseph Schwartz  •  Beth H. Shaz Editors

Best Practices in Processing and Storage for Hematopoietic Cell Transplantation

Editors Joseph Schwartz Department of Pathology & Cell Biology Columbia University New York, NY USA

Beth H. Shaz New York Blood Center New York, NY USA

Advances and Controversies in Hematopoietic Transplantation and Cell Therapy ISBN 978-3-319-58948-0    ISBN 978-3-319-58949-7 (eBook) https://doi.org/10.1007/978-3-319-58949-7 Library of Congress Control Number: 2017961856 © Springer International Publishing AG 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Contents

1 Journey of Hematopoietic Cells: Processing to Infusion����������������������    1 Beth Shaz and Joseph Schwartz 2 Regulations and Accreditation of Processing Laboratories����������������    5 Yvette C. Tanhehco and Joseph Schwartz Part 1  HPC, Apheresis and HPC, Marrow 3 Donor Qualification for Hematopoietic Cell Transplantation ������������   23 Patricia Shi 4 Routine Hematopoietic Progenitor Cell Processing: HPC, Apheresis and HPC, Marrow Products ��������������������������������������   37 Jay S