Bi-atrial function and its relation with biventricular function and clinical parameters in patients operated for tetralo
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POSTER PRESENTATION
Open Access
Bi-atrial function and its relation with biventricular function and clinical parameters in patients operated for tetralogy of Fallot Saskia E Luijnenburg1,2*, Rosanne Peters1, Rob J van der Geest3, Adriaan Moelker2, Jolien W Roos-Hesselink4, Yolanda B de Rijke5, Hubert W Vliegen6, Barbara J Mulder7, Willem A Helbing1,2 From 15th Annual SCMR Scientific Sessions Orlando, FL, USA. 2-5 February 2012 Background Biventricular size and function have been studied extensively in patients after tetralogy of Fallot (TOF) repair, but little is known about atrial size and function. The atria play a crucial role in ventricular filling during diastole, and abnormalities in atrial size and function may reflect ventricular diastolic dysfunction. Diastolic dysfunction may precede systolic dysfunction and may therefore play an important role in the early detection of ventricular dysfunction. Aim
We assessed bi-atrial size and function in patients after TOF repair, and evaluated relationships with biventricular systolic and diastolic function, and clinical parameters.
Methods 51 patients (21±8 years) and 30 healthy controls (31±7 years) were included and underwent magnetic resonance imaging. Patients also underwent exercise testing, and biomarker assessment. Bi-atrial and biventricular size, systolic and diastolic function were assessed from timevolume curves (figure 1) and time-volume-change curves. Results In patients, right atrial (RA) minimal volume (min.vol.), RA pump function, and RA late emptying fraction were increased (RA min.vol.: 34±8 ml/m2 (patients) vs. 28±8 ml/m2 (controls), p=0.001); RA reservoir function, RA 1
Pediatric Cardiology, Erasmus Medical Center - Sophia Children’s Hospital, Rotterdam, Netherlands Full list of author information is available at the end of the article
early emptying fraction, and the RA early-to-late-emptying ratio (E/A ratio) were decreased (RA E/A ratio: 1.1 ±0.5 (patients) vs. 1.9±0.9 (controls), p
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