Bio-inspired Polyphenolic Adhesives for Medical and Technical Applications

Nature has been developing adhesives for millions of years, mankind for just a few thousands of years. For this reason it is worth having a closer look at what nature does and how we can develop bio-inspired adhesives for technical and medical application

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Bio-inspired Polyphenolic Adhesives for Medical and Technical Applications Klaus Rischka, Katharina Richter, Andreas Hartwig, Maria Kozielec, Klaus Slenzka, Robert Sader and Ingo Grunwald

Contents Introduction (Katharina Richter and Ingo Grunwald) 13.2 Phenolic Adhesives in Mytilus edulis (Klaus Rischka and Katharina Richter) 13.3 Synthetic Phenolic Resins and Their Applications (Andreas Hartwig) 13.4 Tannins and Their Application in Adhesives (Maria Kozielec and Klaus Rischka) 13.5 Phenolic Adhesives for Medical Applications (Robert Sader and Ingo Grunwald) 13.6 Special Applications: Space Exploration (Klaus Slenzka) 13.7 Conclusion Acknowledgment References

13.1 Introduction (Katharina Richter and Ingo Grunwald)

13.1

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Nature has been developing adhesives for millions of years, mankind for just a few thousands of years. For this reason it is worth having a closer look at what nature does and how we can develop bio-inspired adhesives for technical and medical applications. Some examples of natural materials which have already been used for technical adhesives are casein, latex rubber, tree gum, and adhesives derived from natural sources used for the waterproofing of natural textiles, the production of paper, and the sealing of jars (Papov et al., 1995; Creton and Papon, 2003). Bio-inspired adhesives can be found in all areas of the natural world. Because of their origin, those adhesives are also called biological adhesives or bioadhesives and they fulfill several different functions (Smith and Callow, 2006; Carrington, 2008; Antonietti and Fratzl, 2010). Plants use adhesives, for example, for self-healing and for protecting themselves against wood defects, while animals use sticky materials for protecting themselves against predators and for hunting prey (Keckes et al., 2003; Schreiber et al., 2005; Flammang, 2006; Voigt and Gorb, 2008; Plaza et al., 2009). Microorganisms use adhesive material for settlement, surface attachment, and colonization (Melzer et al., 2008; Flammang et al., 2009; Santos et al., 2009; Scholz et al., 2009). Higher organisms, such as humans, rely on an inducible adhesive system: the wound healing promoter fibrinogen ((Berlind et al., 2010), which is discussed in detail in Chapter 15, p. 225 of this book). One important advantage of nearly all kinds of bioadhesives is independence from the need for surface preparation and special curing conditions, for example 150°C and more for some epoxy resins. The substrates do not need to be freed from humidity and do not require special activation, as often do substrates for technical adhesives.

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In addition, something which is difficult to realize for a technical adhesive but which can be easily done in nature is bonding in the presence of water or even underwater (Holten-Andersen and Waite, 2008). The advantages of these bioadhesives are due to their special chemical composition. One class of chemical compound which one frequently finds in bioadhesives are polyphenolic molecules. These molecules are not on