Bioactive Natural Products for the Management of Cancer: from Bench to Bedside
This book illustrates the importance of the Natural Biometabolites, which offer a rich reservoir of candidate compounds for drug discovery in the battle against cancer. Recent research and development efforts concerning anti-cancer drugs derived from natu
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Bioactive Natural Products for the Management of Cancer: from Bench to Bedside
Bioactive Natural Products for the Management of Cancer: from Bench to Bedside
Anil K. Sharma Editor
Bioactive Natural Products for the Management of Cancer: from Bench to Bedside
Editor Anil K. Sharma Department of Biotechnology Maharishi Markandeshwar (Deemed to be University) Mullana Ambala, Haryana, India
ISBN 978-981-13-7606-1 ISBN 978-981-13-7607-8 (eBook) https://doi.org/10.1007/978-981-13-7607-8 © Springer Nature Singapore Pte Ltd. 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore
Preface
Natural biometabolites have been the mainstay of cancer chemotherapy, being a rich reservoir of candidate compounds for drug discovery. Recent efforts into the research and development of anticancer drugs derived from natural products have led to the identification of a variety of candidate molecules that inhibit cancer cell proliferation and metastasis via various mechanisms. With the advent of new technologies such as combinatorial chemistry and high-throughput screening, next- generation sequencing, and the ease of identifying abnormal genes, it is now possible to consider that natural products would sound the death knell for cancer. Moreover, natural products are likely to provide novel lead molecules which would be used as templates for restructuring them for potential anticancer drug candidates with enhanced biological properties. Moreover, nanomedicine-based natural products have recently shown promising therapeutic effects with better efficacy and target specificity against cancer countering drug resistance as well. Despite the increasing interest in natural product rese
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