Bioinformatics for Comparative Proteomics
With the rapid development of proteomic technologies in the life sciences and in clinical applications, many bioinformatics methodologies, databases, and software tools have been developed to support comparative proteomics study. In Bioinformatics for Com
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Bioinformatics for Comparative Proteomics Edited by Cathy H. Wu Chuming Chen
Methods
in
Molecular Biology™
Series Editor John M. Walker School of Life Sciences University of Hertfordshire Hatfield, Hertfordshire, AL10 9AB, UK
For other titles published in this series, go to www.springer.com/series/7651
Bioinformatics for Comparative Proteomics Edited by
Cathy H. Wu Department of Computer and Information Sciences, Center for Bioinformatics and Computational Biology, University of Delaware, Newark, DE, USA
Chuming Chen Department of Computer and Information Sciences, Center for Bioinformatics and Computational Biology, University of Delaware, Newark, DE, USA
Editors Cathy H. Wu, Ph.D. Center for Bioinformatics and Computational Biology University of Delaware 15 Innovation Way, Suite 205 Newark, DE 19711 USA [email protected]
Chuming Chen, Ph.D. Center for Bioinformatics and Computational Biology University of Delaware 15 Innovation Way, Suite 205 Newark, DE 19711 USA [email protected]
ISSN 1064-3745 e-ISSN 1940-6029 ISBN 978-1-60761-976-5 e-ISBN 978-1-60761-977-2 DOI 10.1007/978-1-60761-977-2 Springer New York Dordrecht Heidelberg London © Springer Science+Business Media, LLC 2011 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Humana Press, c/o Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Humana Press is part of Springer Science+Business Media (www.springer.com)
Preface With the rapid development of proteomic technologies in life sciences and in clinical applications, many bioinformatics methodologies, databases, and software tools have been developed to support comparative proteomics study. This volume aims to highlight the current status, challenges, open problems, and future trends in developing bioinformatics tools and resources for comparative proteomics research and to serve as a definitive source of reference providing both the breadth and depth needed on the subject of Bioinformatics for Comparative Proteomics. The volume is structured to introduce three major areas of research methods: (1) bas
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