Bioinformatics in MicroRNA Research

This thorough volume provides an in-depth introduction to and discussion of microRNAs (miRs) and their targets, miR functions, and computational techniques applied in miR research, thus serving the need for a comprehensive book focusing on miR target gene

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Jingshan Huang · Glen M. Borchert Dejing Dou · Jun (Luke) Huan Wenjun Lan · Ming Tan · Bin Wu Editors

Bioinformatics in MicroRNA Research

Methods

in

Molecular Biology

Series Editor: John M. Walker School of Life and Medical Sciences University of Hertfordshire Hatfield, Hertfordshire, AL10 9AB, UK

For further volumes: http://www.springer.com/series/7651

Bioinformatics in MicroRNA Research Editors

Jingshan Huang School of Computing, University of South Alabama, Mobile, AL, USA

Glen M. Borchert Department of Pharmacology, University of South Alabama, Mobile, AL, USA; Department of Biology, University of South Alabama, Mobile, AL, USA

Dejing Dou Department of Computer and Information Science, University of Oregon, Eugene, OR, USA

Jun (Luke) Huan Department of Electrical Engineering and Computer Science, University of Kansas, Lawrence, KS, USA

Wenjun Lan School of Bio-Engineering, Qilu University of Technology, Jinan, Shandong, China

Ming Tan Mitchel Cancer Institute, University of South Alabama, Mobile, AL, USA

Bin Wu Department of Endocrinology, First Affiliated Hospital, Kunming Medical University, Kunming, Yunnan, China

Editors Jingshan Huang School of Computing University of South Alabama Mobile, AL, USA Dejing Dou Department of Computer   and Information Science University of Oregon Eugene, OR, USA Wenjun Lan School of Bioengineering Qilu University of Technology Jinan, Shandong, China Bin Wu Department of Endocrinology First Affiliated Hospital Kunming Medical University Kunming, Yunnan, China

Glen M. Borchert Department of Pharmacology University of South Alabama Mobile, AL, USA Department of Biology University of South Alabama Mobile, AL, USA Jun (Luke) Huan Department of Electrical Engineering   and Computer Science University of Kansas Lawrence, KS, USA Ming Tan Mitchel Cancer Institute University of South Alabama Mobile, AL, USA

ISSN 1064-3745     ISSN 1940-6029 (electronic) Methods in Molecular Biology ISBN 978-1-4939-7044-5 ISBN 978-1-4939-7046-9  (eBook) DOI 10.1007/978-1-4939-7046-9 Library of Congress Control Number: 2017937362 © Springer Science+Business Media LLC 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the p