Bioreactors for Tissue Engineering Principles, Design and Operation
For the first time in a single volume, the design, characterisation and operation of the bioreactor system in which the tissue is grown is detailed. Bioreactors for Tissue Engineering presents an overall picture of the current state of knowledge in the en
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Bioreactors for Tissue Engineering Principles, Design and Operation
Edited by
JULIAN CHAUDHURI University of Bath, U.K. and
MOHAMED AL-RUBEAI University College Dublin, Ireland
A C.I.P. Catalogue record for this book is available from the Library of Congress.
ISBN-10 ISBN-13 ISBN-10 ISBN-13
1-4020-3740-6 (HB) 978-1-4020-3740-5 (HB) 1-4020-3741-4 (e-book) 978-1-4020-3741-2 (e-book)
Published by Springer, P.O. Box 17, 3300 AA Dordrecht, The Netherlands. www.springeronline.com
Legend for front cover photographs: Upper left: Fibroblast cells growing on a collagen matrix Upper right: Schematic of the pulsatile tissue engineered heart valve bioreactor Lower left: Minibioreactor perfusion chamber Lower right: Scanning electron micrograph of a poly(lactic acid-co-glycolic acid) hollow fiber
Printed on acid-free paper
All Rights Reserved © 2005 Springer No part of this work may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording or otherwise, without written permission from the Publisher, with the exception of any material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Printed in the Netherlands.
TABLE OF CONTENTS Preface
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BIOREACTOR SYSTEMS FOR TISSUE ENGINEERING: A FOUR-DIMENSIONAL CHALLENGE M. Ellis, M. Jarman-Smith and J.B.Chaudhuri MICROREACTOR OPTIMISATION FOR FUNCTIONAL TISSUE ENGINEERING W.W. Minuth, R. Strehl and K. Schumacher TAYLOR-VORTEX BIOREACTORS FOR ENCHANCED MASS TRANSPORT S.J. Curran and R.A. Black PACKED BED BIOREACTORS J.N. Warnock, K. Bratch and M. Al-Rubeai DESIGN AND OPERATION OF A RADIAL FLOW BIOREACTOR FOR RECONSTRUCTION OF CULTURE TISSUES M. Kino-Oka and M. Taya CARTILAGE GROWTH IN MAGNETIC RESONANCE MICROSCOPY-COMPATIBLE HOLLOW FIBER BIOREACTORS J.B. Greco and R.G. Spencer MECHANICAL CONDITIONING OF CELL-SEEDED CONSTRUCTS FOR SOFT TISSUE REPAIR – ARE OPTIMISATION STRATEGIES POSSIBLE? D.L. Bader and D.A. Lee MECHANICAL BIOREACTORS FOR BONE TISSUE ENGINEERING S.H. Cartmell and A.J. El Haj A DYNAMIC STRAINING BIOREACTOR FOR COLLAGENBASED TISSUE ENGINEERING Y. Shi and I. Vesely BIOREACTORS FOR LIGAMENT ENGINEERING B.J. Ainsworth and J.B. Chaudhuri BIOMECHANICAL CONSIDERATIONS FOR TISSUE ENGINEERED HEART VALVE BIOREACTORS M.S. Sacks, G.C. Engelmayr Jr., D.K. Hildebrand and J.E. Mayer Jr.
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DESIGN OF VASCULAR GRAFT BIOREACTORS P.S. McFebridge and J.B. Chaudhuri PERFUSION BIOREACTORS FOR CARDIOVASCULAR TISSUE ENGINEERING V. Kasyanov, J.J. Sistino, T.C. Trusk, R.R. Markwald and V. Mironov HAEMATOPOIETIC CULTURE SYSTEMS L. Safina, N. Panoskaltsis and A. Mantalaris MONITORING THE PERFORMANCE OF TISSUE ENGINEERING BIORACTORS USING MAGNETIC RESONANCE IMAGING AND SPECTROSCOPY A.A. Neves and K.M. Brindle CRYOPRESERVATION OF HEPATOCYTES FOR BIOARTIFICIAL LIVER DEVICES M.H. Grant and D. Stevenson
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