BMI, functional and cognitive status in a cohort of nonagenarians: results from the Mugello study
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RESEARCH PAPER
BMI, functional and cognitive status in a cohort of nonagenarians: results from the Mugello study Monica Dinu1 · Barbara Colombini1 · Giuditta Pagliai1 · Federica Vannetti2 · Guido Pasquini2 · Raffaello Molino Lova2 · Francesca Cecchi2 · Sandro Sorbi2 · Francesco Sofi1,2 · Claudio Macchi2 · The Mugello Study Working Group Received: 28 July 2020 / Accepted: 7 October 2020 © The Author(s) 2020
Key summary points Aim Our aim was to investigate the association of body mass index (BMI) with functional and cognitive status in a group of nonagenarians. Findings By grouping the participants according to BMI categories, overweight and obese participants showed lower functional capability, higher risk of falling but better Mini-Mental State Examination (MMSE) performance than participants with normal weight or underweight. Message This cross-sectional survey supports the hypothesis that adiposity could affect the cognitive state of people reaching the old age. Abstract Purpose The study of the relationship between body weight and health in old age has attracted increasing interest. The aim of the present study is to investigate the association of body mass index (BMI) with functional and cognitive status in a group of nonagenarians. Methods We analyzed 475 participants (348 women, 127 men; median age 92 years) from the Mugello study. Participants were evaluated through laboratory, instrumental examinations and questionnaires. Results By grouping the participants according to BMI categories, a better perception of health and nutritional status and a lower prevalence of sarcopenia (p
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