Brain Network Connectivity and the Choice Motor Reaction in Combatants with Mild Traumatic Brain Injuries
- PDF / 4,441,147 Bytes
- 11 Pages / 594 x 792 pts Page_size
- 8 Downloads / 181 Views
Neurophysiology, Vol. 52, No. 3, May, 2020
Brain Network Connectivity and the Choice Motor Reaction in Combatants with Mild Traumatic Brain Injuries N. B. Filimonova,1 M. Yu. Makarchuk,1 I. G. Zyma,1 V. V. Kal’nysh,2 and A. F. Cheburkova1 Received May 19, 2019 We examined times (latencies) of two types of the sensorimotor (visuomotor) reactions, simple senso rimotor reaction (SSMR) and choice motor reaction (ChMR), in men (combatants) suffering from the consequences of mild traumatic brain injury (mTBI) during the Joint Forces Operation in the East of Ukraine (17 right-handed volunteers aged 27–43 years) and compared the respective values with those demonstrated by healthy control men (16 right-handed volunteers, 18–21 years). Combatants with mTBI were characterized by significantly greater values of the latency in the ChMR, mostly determined by considerably longer times necessary for decision-making processes. Results of the analysis of cerebral network connectivity based on the data of EEG recording, coherence measurements, and LORETA neurovisualization gave reasons to suppose that a large-scale synchronized frontoparietal neuronetwork functions in control subjects; this network is responsible for decision making according to the results of control, analysis of information, and coordination of various alternatives. Unlike this, an associative decision-making system mostly functions in combatants with mTBI; this system uses coding networks in the primary and secondary visual cortices; functioning of the above associative system is followed by the creation of imaginary phenomena and associations, which are then realized in motor acts.
Keywords: mild traumatic brain injury (mTBI), simple sensorimotor reaction (SSMR), choice motor reaction (ChMR), concussion, EEG, coherence, LORETA, neurovisualization.
INTRODUCTION Mild traumatic brain injury (mTBI) results in damage of the brain structures, alteration of cerebral blood supply, and that of liquor circulation. It leads to significant changes in the neurodynamics and modifications of the cognitive functions. Mild TBIs have become common in today Ukraine because of the armed conflict in the Eastern regions of Ukraine resulting from Russian aggression. Unfortunately, consequences of both contusions and concussions received in the course of the armed conflict attracted insufficient attention despite their vast prevalence and significant long-term negative effects on cognitive functions of the patients. Moreover, the network connectivity in the brains of people with
Taras Shevchenko National University of Kyiv, Kyiv, Ukraine; Kundiiev Institute of Occupational Health of the National Academy of Medical Sciences of Ukraine, Kyiv, Ukraine. Correspondence should be addressed to M. Makarchuk (e-mail: [email protected]). 1 2
mTBI during the performance of various cognitive tasks has also been insufficiently studied. From this aspect, of great interest is the performance of simple sensorimotor reactions (SSMRs) and choice motor reactions (ChMRs); abnormal delays o
Data Loading...
