Calcium/vitamin D
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Hypercalcaemia with secondary tumoral calcinosis: case report A 43-year-old woman developed hypercalcaemia with secondary tumoral calcinosis following long term treatment with calcium and vitamin D for hypoparathyroidism [durations of treatment to reactions onset and outcomes not stated]. The woman presented to a hospital with a growing swelling on the dorsal side of the right foot for a few months. The tumefaction was inflammatory and hard without skin injury. She had a history of thyroidectomy with secondary hypoparathyroidism, which was treated with vitamin D and calcium [dosages and routes not stated] supplementation for years. The investigations showed renal failure associated with hypercalcaemia. A radiograph showed amorphous and multilobulated calcifications (4 × 4.5cm) in a periarticular distribution around the base of the third toe, showing a "faveolate" or "cloud-like" aspect with respect to the cortical bone. Her CT scan revealed equally hydrocalcic levels formed into the lobules. The MRI showed a soft mass infiltrating the adjacent muscles along with hyposignal in T1-weighted sequences and partitioning of the lesion within the hyposignal zone. The woman underwent surgical excision and pathological analysis suggested calcinosis without malignancy. Author comment: "Cases of iatrogenic hypercalcaemia with secondary renal chronic failure in the context of postsurgical hypoparathyroidism have been described, but to our knowledge this is the first case with presence of secondary tumoral calcinosis." Sondag M, et al. Secondary Calcinosis of the Foot. The Journal of Rheumatology 45: 143-144, No. 1, Jan 2018. Available from: URL: http://doi.org/10.3899/ 803438447 jrheum.170277 - France
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Reactions 7 Dec 2019 No. 1782
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