Cardiac magnetic resonance imaging demonstrates biatrial stunning after catheter ablation of persistent atrial fibrillat

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Cardiac magnetic resonance imaging demonstrates biatrial stunning after catheter ablation of persistent atrial fibrillation Kai Muellerleile1*, Michael Groth2, Daniel Steven1, Boris Hoffmann1, Jakob Lueker1, Arian Sultan1, Ulf K Radunski1, Gunnar Lund2, Gerhard Adam2, Thomas Rostock1, Stephan Willems1 From 15th Annual SCMR Scientific Sessions Orlando, FL, USA. 2-5 February 2012 Summary This study evaluated the course of active left atrial (LA), LA appendage (LAA) and right atrial (RA) emptying with respect to ablation-related inflammation after persistent AF ablation by cardiac magnetic resonance imaging (CMR). Background Catheter ablation of persistent atrial fibrillation (AF) aims at reestablishing active atrial emptying. However, little is known on recovery of active atrial emptying and inflammation after successful ablation of persistent AF. Methods CMR was performed in 19 consecutive patients at baseline (BL) within 24 hours and at follow-up (FU) 5±2 months after restoration of sinus rhythm by catheter ablation of persistent AF. Velocity encoded (VENC) MRI was used to assess active LA, LAA and RA emptying: Active LA and RA emptying were quantified by calculating the active emptying fraction (AEF) from transmitral VENC-MRI flow profiles. LAA function was quantified by measurements of peak a-wave velocities from VENC-MRI flow profiles perpendicular to the LAA orifice. Peri-atrial inflammation was assessed using edema-sensitive black-blood T2-weighted MRI. Results There was a significant increase in LA-AEF from 17 (1226) % at baseline to 25 (23-36) % at follow-up (p