• PDF / 182,764 Bytes
• 1 Pages / 595.245 x 841.846 pts (A4) Page_size
• 60 Downloads / 129 Views

DOWNLOAD

REPORT

---

1 S

Nosocomial Chryseobacterium indologenes bacteremia and lack of efficacy: case report. A 59-year-old man developed nosocomial Chryseobacterium indologenes bacteremia during treatment with cefepime/tazobactam for Escherichia coli. Additionally, he exhibited lack of efficacy to levofloxacin and minocycline [routes and dosages not stated]. The man had a moderately differentiated left lung squamous cell carcinoma. He had metastasis to bone, liver, brain, left adrenal gland, subcutaneous tissue in chest and back, mediastinal, bilateral axillary and right cardiophrenic angle and lymph nodes including right pulmonary hilar. Cytokeratin 7 tumour marker was positive. He was hospitalised due to generalised weakness and loss of appetite since 3-4 days. He was scheduled to undergo palliative external beam radiotherapy and unspecified systemic chemotherapy. He had low haemoglobin 7 gm/dL and received RBC transfusion. Due to low glasgow coma scale (GCS) he was transferred to ICU. He had high total leucocyte count, dyselectrolytemia, thrombocytopenia, hypernatraemia, deranged kidney function test and hypokalaemia. Subsequently, he was found to have multi-drug resistant Escherichia coli. He was started on cefepime/tazobactam injection for 10 days and polymyxin-B injection for 6 days. After 1 week of ICU admission, aerobic blood sample cultures revealed bacteremia due to Chryseobacterium indolegenes. On the basis of culture reports, levofloxacin and minocycline were added, and polymyxin B was stopped. Minocycline was continued for 9 days and levofloxacin for 11 days. On day 20 of ICU admission, his condition worsened with worsening GCS and sensorium. Subsequently, he developed aspiration, dyselectrolytaemia and sepsis that was refractory to antibiotics, and he was placed on non-invasive ventilation. However, he developed cardiopulmonary arrest secondary to an episode of bradycardia. Bhagawati G, et al. Bacteraemia by Chryseobacterium indologenes in a patient with lung cancer: A clinical and microbiological investigation. Indian Journal of Critical Care Medicine 23: 157-159, No. 3, Mar 2019. Available from: URL: https://www.ijccm.org/doi/IJCCM/pdf/10.5005/jp-journals-10071-23142 803503494

0114-9954/20/1823-0001/$14.95 Adis © 2020 Springer Nature Switzerland AG. All rights reserved

Reactions 26 Sep 2020 No. 1823