• PDF / 169,660 Bytes
• 1 Pages / 595.245 x 841.846 pts (A4) Page_size
• 60 Downloads / 157 Views

DOWNLOAD

REPORT

---

1 S

Anaphylactic reaction and lack of efficacy: case report A 47-year-old woman developed anaphylactic reaction in the form of lip angioedema during treatment with cefuroxime and clarithromycin. Additionally, she experienced lack of efficacy following treatment with epinephrine for the anaphylactic reaction [durations of treatments to reaction onset not stated; not all indications, routes and dosages stated] The woman, who developed lip angioedema, presented with the suspicion of allergic reactions to cefuroxime, clarithromycin and sulfa-based medications (unspecified) for evaluation of her allergy. Subsequently, she was intradermally tested to a dose of 10 mg/mL of cefuroxime, and a flare response of 15mm was noted. Within minutes, she felt unwell with generalised erythema, pruritus and dizziness. Based on this, she was diagnosed with an anaphylactic reaction. Therefore, the woman was initially treated with IM epinephrine 0.5mg. She obtained a minimal response initially, and later, she remained unwell. Her systolic BP decreased to 105mm Hg from initial BP of 145 mmHg. She was then placed in a supine position with raised legs and received normal saline for resuscitation. Additionally, she received oxygen and diphenhydramine. Subsequently, her BP raised to 135mm Hg. She was then shifted to the emergency room for further monitoring, and further, no events were observed. Wardha W, et al. Playing with fire: The risks associated with intradermal cephalosporin testing. Allergy, Asthma and Clinical Immunology 16 (Suppl. 1): abstr. 33, 2020. 803515269 Available from: URL: http://doi.org/10.1186/s13223-020-00445-x [abstract]

0114-9954/20/1830-0001/$14.95 Adis © 2020 Springer Nature Switzerland AG. All rights reserved

Reactions 14 Nov 2020 No. 1830