Cefuroxime/eculizumab

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Candida albicans peritonitis: case report A 29-years-old woman developed acute Candida albicans peritonitis during treatment with eculizumab and cefuroxime [dosages and routes not stated]. The woman, who had end-stage renal disease, had been receiving eculizumab for atypical haemolytic uraemic syndrome. Subsequently, she presented to the catheterisation lab for elective peritoneal dialysis catheter placement. She received cefuroxime as antibacterial prophylaxis. However, within 24 hours of the procedure, she was admitted due to abdominal pain, severe nausea, vomiting and chills. Her peritoneal fluid analysis was consistent with peritonitis, and the peritoneal fluid culture grew Candida albicans within 26 hours. The woman’s peritoneal dialysis catheter was removed and she was treated with unspecified antifungal therapy. Thereafter, her abdominal pain improved. She was then discharged on fluconazole. Han H, et al. Acute Candida albicans Peritonitis in a Patient with Atypical Hemolytic Uremic Syndrome Treated with Eculizumab. Peritoneal Dialysis International 39: 803500465 575-576, No. 6, Nov 2019. Available from: URL: http://doi.org/10.3747/pdi.2019.00094

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Reactions 12 Sep 2020 No. 1821

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