Chest CT for early detection and management of coronavirus disease (COVID-19): a report of 314 patients admitted to Emer
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CHEST RADIOLOGY
Chest CT for early detection and management of coronavirus disease (COVID‑19): a report of 314 patients admitted to Emergency Department with suspected pneumonia Cartocci Gaia1 · Colaiacomo Maria Chiara1 · Lanciotti Silvia1 · Andreoli Chiara1 · De Cicco Maria Luisa1 · Brachetti Giulia1 · Pugliese Silvia1 · Capoccia Lucia1 · Tortora Alessandra1 · Scala Annarita1 · Valentini Cristina1 · Almberger Maria1 · D’Aprile Maria Rosaria1 · Avventurieri Giacinta1 · Giura Riccardo1 · Kharrub Zaher1 · Leonardi Andrea1 · Boccia Maddalena2 · Carlo Catalano3 · Ricci Paolo1 Received: 16 April 2020 / Accepted: 19 July 2020 © The Author(s) 2020
Abstract Purpose The purpose of our study was to assess the potential role of chest CT in the early detection of COVID-19 pneumonia and to explore its role in patient management in an adult Italian population admitted to the Emergency Department. Methods Three hundred and fourteen patients presented with clinically suspected COVID-19, from March 3 to 23, 2020, were evaluated with PaO2/FIO2 ratio from arterial blood gas, RT-PCR assay from nasopharyngeal swab sample and chest CT. Patients were classified as COVID-19 negative and COVID-19 positive according to RT-PCR results, considered as a reference. Images were independently evaluated by two radiologists blinded to the RT-PCR results and classified as “CT positive” or “CT negative” for COVID-19, according to CT findings. Results According to RT-PCR results, 152 patients were COVID-19 negative (48%) and 162 were COVID-19 positive (52%). We found substantial agreement between RT-PCR results and CT findings (p
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