Cholestatic Liver Disease

Since the publication of the first edition, there have been advances in both the diagnosis and the management of many of the cholestatic liver diseases. Cholestatic Liver Disease, Second Edition thoroughly updates the topics previously addressed, such as

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Elizabeth J. Carey Keith D. Lindor Editors

Cholestatic Liver Disease Second Edition

CLINICAL GASTROENTEROLOGY

Series Editor George Y. Wu University of Connecticut Health Center, Farmington, CT, USA

For further volumes: http://www.springer.com/series/7672

Elizabeth J. Carey • Keith D. Lindor Editors

Cholestatic Liver Disease Second Edition

Editors Elizabeth J. Carey Division of Gastroenterology and Hepatology Mayo Clinic Phoenix, AZ, USA

Keith D. Lindor Mayo Clinic Phoenix, AZ, USA

ISSN 2197-7399 ISSN 2197-7704 (electronic) ISBN 978-1-4939-1012-0 ISBN 978-1-4939-1013-7 (eBook) DOI 10.1007/978-1-4939-1013-7 Springer New York Heidelberg Dordrecht London Library of Congress Control Number: 2014943498 © Springer Science+Business Media New York 2014 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Humana Press is a brand of Springer Springer is part of Springer Science+Business Media (www.springer.com)

Preface

Despite advances in the understanding and management of the cholestatic liver diseases, these disorders continue to pose clinical challenges to patients and their medical practitioners. This second edition of Cholestatic Liver Disease aims to update the reader on the classic entities of primary biliary cirrhosis and primary sclerosing cholangitis while also providing insights on more recently described problems: IgG4-asso