Chronic kidney disease could be a risk factor for thrombosis in essential thrombocythemia and polycythemia vera

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ORIGINAL ARTICLE

Chronic kidney disease could be a risk factor for thrombosis in essential thrombocythemia and polycythemia vera Ivan Krečak1   · Hrvoje Holik2,3 · Morić Perić Martina4 · Ivan Zekanović4 · Božena Coha2 · Velka Gverić‑Krečak1 Received: 28 February 2020 / Revised: 26 May 2020 / Accepted: 4 June 2020 © Japanese Society of Hematology 2020

Abstract Chronic kidney disease (CKD) is a well-known risk factor for venous thromboembolism and cardiovascular (CV) disease development in the general population, but its role in thrombotic risk in essential thrombocythemia (ET) and polycythemia vera (PV) remains poorly understood. This retrospective multicenter study analyzed clinical correlations and the potential impact of CKD on thrombosis development in ET and PV patients. We included 167 patients (76 ET and 91 PV); 25.7% had CKD at diagnosis, defined as estimated glomerular filtration rate (eGFR)