Climacteric

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patients with vascular risk factors. Their quantification in peripheral blood is a reproducible method of assessing endothelial dysfunction.

Circulating Endothelial Progenitor Cells Definition This term is used to describe a cell population that can be isolated from circulating mononuclear cells, bone marrow, and cord blood. These cells showed expression of various endothelial markers, they have the ability to mature into endothelial cells and have a physiological role in the repair of endothelial lesions. Experimentally, when these cells are injected into animal models with ischemia, they are rapidly incorporated into sites of neovascularization. The levels of circulating endothelial progenitor cells correlate inversely with the degree of endothelial dysfunction in humans at various degrees of cardiovascular risk.

CIS ▶ Clinically Isolated Syndromes

Clan Definition A group of Aboriginal and/or Torres Strait Islander people who share membership of a common language and/or clan or tribal group.

CLASP ▶ Cardiovascular Limitations and Symptoms Profile

Classical Test Theory Synonyms Traditional Psychometric Model; Classical Measurement Model Definition Model of measurement that assumes that items are of broadly similar difficulty, and they are similarly good representatives of the latent construct. Therefore, the more items in a scale, the better the measurement of the latent construct. Items have their response categories to reflect severity or degree of response level. The level on the latent traits results from the direct sum of the responses given to the items.

Classification of Systemic Sclerosis Definition Systemic sclerosis patients are classified according to the extent of skin involvement: limited systemic sclerosis, with no detectable skin involvement (these patients present with Raynaud’s phenomenon and typical capillaroscopic abnormalities and/or systemic sclerosis specific autoantibodies); limited cutaneous systemic sclerosis, with skin involvement essentially limited to the hands and face and diffuse systemic sclerosis, with proximal skin involvement.

CLI ▶ Critical Limb Ischaemia

Climacteric Synonyms Menopause

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Glossary

Definition Climacteric is most often a synonym for female menopause. The climacteric refers to a syndrome of endocrine, somatic and psychological changes occurring at menopause in women.

Clustering Definition Two or more health problems occur consecutively in one person. For example, musculoskeletal pain is often present at multiple sites.

Climatotherapy CMA Definition Climatotherapy is the use of climatic factors such as solar radiation, altitude or sea climate for the treatment of certain disorders.

▶ Cost-Minimization Analysis

Cocaine Clinic-Based Population Definition Study populations that are selected from health care facilities.

Clinical Attack Rate Definition Percentage of the population who become ill from infection by the influenza virus.

Clinical COPD Questionnaire Definition CCQ is a simple short and effective questionnaire for COPD patients, develo