Clinical significance of gadobutrol in magnetic resonance imaging for the detection of myocardial infarction: matched-pa
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Clinical significance of gadobutrol in magnetic resonance imaging for the detection of myocardial infarction: matched‑pair cohort study to compare with gadopentetate dimeglumine at standard dose Kohei Kawasaki1 · Takumi Okubo2 · Tsutomu Nagatari1 · Masanobu Matsumoto1 · Takahiro Kageyama1 Received: 3 December 2019 / Revised: 15 May 2020 / Accepted: 21 May 2020 © Japanese Society of Radiological Technology and Japan Society of Medical Physics 2020
Abstract We aimed to confirm whether gadobutrol is more useful for late gadolinium enhancement (LGE) imaging than gadopentetate dimeglumine (Gd-DTPA) at the standard dose. Patients who underwent LGE imaging to assess myocardial infarction were retrospectively enrolled: gadobutrol, 51 cases; Gd-DTPA, 49 cases. Contrast ratios of infarcted lesion to remote myocardium (CRremote) and to left ventricular blood (CRblood) were compared. Patient characteristics that might affect image contrast did not differ between groups. C Rremote (median, (interquartile range)) at 10 and 15 min after administration was 0.79 (0.08) and 0.70 (0.09) for gadobutrol, and 0.74 (0.13) and 0.65 (0.16) for Gd-DTPA (P
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