Clobetasol/fluticasone-propionate

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Clobetasol/fluticasone-propionate Central-serous-chorioretinopathy: case report

A 48-year-old man developed central serous chorioretinopathy (CSCR) during treatment with clobetasol and fluticasone propionate for psoriasis [dosages and durations of treatments to reaction onset not stated]. The man had psoriasis, and he had been receiving intermittent topical clobetasol for psoriasis flare that had occurred recently. Subsequently, he presented with a new-onset blurred vision in the left eye following topical application of clobetasol to the periauricular skin, tip of his nose and eyebrows. On retinal evaluation, he was observed to have CSCR in the left eye, with visual acuity loss that was not significant. In addition to topical clobetasol, he had received fluticasone propionate nasal spray and azelastine hydrochloride. At the current presentation, the topical and intranasal steroids were discontinued. At 2-month follow-up, the subretinal fluid accumulation associated with CSCR resolved. The treatment with clobetasol was re-initiated after 6 months. However, CSCR relapsed after 2 weeks of clobetasol treatment. Once again clobetasol was discontinued, and the subretinal fluid accumulation resolved. Hilton T, et al. Topical dermal steroid-induced retinopathy. JAAD Case Reports 6: 868-870, No. 9, Sep 2020. Available from: URL: http://doi.org/10.1016/ j.jdcr.2020.07.015

0114-9954/20/1821-0001/$14.95 Adis © 2020 Springer Nature Switzerland AG. All rights reserved

803500796

Reactions 12 Sep 2020 No. 1821

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