Combining whispering gallery mode lasers and microstructured optical fibers: limitations, applications and perspectives

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Combining whispering gallery mode lasers and microstructured optical bers: limitations, applications and perspectives for in-vivo biosensing Alexandre François, Tess Reynolds, Nicolas Riesen, Jonathan M. M. Hall, Matthew R. Henderson, Enming Zhao, Shahraam Afshar V. and Tanya M. Monro MRS Advances / FirstView Article / May 2016, pp 1 - 12 DOI: 10.1557/adv.2016.342, Published online: 12 May 2016

Link to this article: http://journals.cambridge.org/abstract_S205985211600342X How to cite this article: Alexandre François, Tess Reynolds, Nicolas Riesen, Jonathan M. M. Hall, Matthew R. Henderson, Enming Zhao, Shahraam Afshar V. and Tanya M. Monro Combining whispering gallery mode lasers and microstructured optical bers: limitations, applications and perspectives for in-vivo biosensing. MRS Advances, Available on CJO 2016 doi:10.1557/adv.2016.342 Request Permissions : Click here

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MRS Advances © 2016 Materials Research Society DOI: 10.1557/adv.2016.342

Combining whispering gallery mode lasers and microstructured optical fibers: limitations, applications and perspectives for in-vivo biosensing Alexandre François,1, 2 Tess Reynolds,2 Nicolas Riesen,2 Jonathan M. M. Hall,2 Matthew R. Henderson,2 Enming Zhao,2,3 Shahraam Afshar V.1, 2 and Tanya M. Monro1, 2 1 University of South Australia, Adelaide SA 5000, Australia 2 The Institute for Photonics and Advanced Sensing (IPAS), The University of Adelaide, Adelaide SA 5005, Australia 3 Key Lab of In-fiber Integrated Optics, Ministry Education of China, Harbin Engineering University, China ABSTRACT Whispering gallery modes (WGMs) have been widely studied over the past 20 years for various applications, including biological sensing. While the WGM-based sensing approaches reported in the literature have shown tremendous performance down to single molecule detection, at present such sensing technologies are not yet mature and still have significant practical constraints that limit their use in real-world applications. Our work has focused on developing a practical, yet effective, WGM-based sensing platform capable of being used as a dip sensor for in-vivo biosensing by combining WGM fluorescent microresonators with silica Microstructured Optical Fibers (MOFs). We recently demonstrated that a suspended core MOF with a dye-doped polymer microresonator supporting WGMs positioned onto the tip of the fiber, can be used as a dip sensor. In this architecture the resonator is anchored to one of the MOF air holes, in contact with the fiber core, enabling a significant portion of the evanescent field from the fiber to overlap with the sphere and hence excite the fluorescent WGMs. This architecture allows for remote excitation and collection of the WGMs. The fiber also permits easy manipulation of the microresonator for dip sensing applications, and hence alleviates the need for a co