Comment on "Assessment of cerebral glucose metabolism in patients with heart failure by 18F-FDG PET/CT imaging"
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Cardiol 1071-3581/$34.00 Copyright Ó 2020 American Society of Nuclear Cardiology.
enced by increased serum glucose levels before cerebral FDG-PET imaging2 while glucose loading procedure should be prepared before cardiac FDG-PET3. Therefore, two different protocol is required. Two separate injections of FDG and scans seem necessary. However, the procedure demonstrated from the flow chart in Figure 1 contradicted the method in the article. Secondly, it is not clear that how healthy volunteers were involved in the study. Only brain scan data were demonstrated. Whether cardiac scan is performed for this normal control group is not introduced. The baseline characteristic data for this group are also lacking. Method of this study needs to be clarified.
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Qian Wang, MDa Department of Nuclear Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing, China
Journal of Nuclear CardiologyÒ Comment on ‘‘Assessment of cerebral glucose metabolism in patients with heart failure by 18F-FDG PET/CT imaging’’
Figure 1. Flow chart of patient disposition. A total of 198 patients with ischemic cardiac disease (IHD); who underwent gated cardiac 99mTc-sestamibi SPECT/CT MPI at rest, as well as cardiac 18 F-FDG PET/CT and brain 18F-FDG PET/CT scans, and 102 eligible heart failure patients were prospectively recruited for this current study. Biochemistry analysis was also performed. LVEF (%) and the extent of hibernating myocardium (HM%), as well as whole brain metabolic activity (SUV) and brain to cerebellum uptake ratio (SUVR) in the specific brain regions were determined by regions of interest (ROI) analysis.
References 1. Yun M, Nie B, Wen W, Zhu Z, Liu H, Nie S, Lanzenberger R, Wei Y, Hacker M, Shan B, Schelbert HR, Li X, Zhang X (2020) Assessment of cerebral glucose metabolism in patients with heart failure by 18F-FDG PET/CT imaging. J Nucl Cardiol. https://doi. org/10.1007/s12350-020-02258-2 2. Varrone A, Asenbaum S, Vander Borght T, Booij J, Nobili F, Nagren K, Darcourt J, Kapucu OL, Tatsch K, Bartenstein P, Van
Laere K (2009) Eanm procedure guidelines for pet brain imaging using [F-18]FDG, version 2. Eur J Nucl Med Mol 36:2103-2110 3. Dilsizian V, Bacharach SL, Beanlands RS, Bergmann SR, Delbeke D, Dorbala S, Gropler RJ, Knuuti J, Schelbert HR, Travin MI (2016) Asnc imaging guidelines/snmmi procedure standard for positron emission tomography (pet) nuclear cardiology procedures. J Nucl Cardiol 23:1187-1226 doi:10.1007/s12350-020-02410-y Publisher’s Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
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