Common Cold
The common cold is unlike any other human disease. It seems impossible to defeat and affects all of us on a regular basis. Due to the large number of viruses causing colds any specific cure is a major challenge. This unique book brings together a wide ran
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Series Editors Axel Schmidt, University Witten/Herdecke, Faculty of Medicine, AlfredHerrhausen-Str. 50, 58448 Witten, Germany Olaf Weber, Rheinische Friedrich-Wilhelms-Universität, Institute of Molecular Medicine, and Experimental Immunology, Sigmund-FreudStraße 25, 53105 Bonn, Germany Stefan H.E. Kaufmann, Max-Planck-Institut für Infektionsbiologie, Department of Immunology, Charitéplatz 1, 10117 Berlin, Germany
Advisory Board Manfred H. Wolff, University Witten/Herdecke, Germany
Common Cold Ronald Eccles Olaf Weber Editors
Birkhäuser Basel · Boston · Berlin
Editors Ronald Eccles Common Cold Centre Cardiff School of Biosciences Cardiff University Museum Avenue Cardiff CF10 3AX UK
Olaf Weber Rheinische Friedrich-Wilhelms-Universität Institute of Molecular Medicine and Experimental Immunology Sigmund-Freud-Straße 25 53105 Bonn Germany
Library of Congress Control Number: 2009928444 Bibliographic information published by Die Deutsche Bibliothek Die Deutsche Bibliothek lists this publication in the Deutsche Nationalbibliografie; detailed bibliographic data is available in the internet at http://dnb.ddb.de
ISBN 978-3-7643-9894-1 Birkhäuser Verlag, Basel - Boston - Berlin The publisher and editor can give no guarantee for the information on drug dosage and administration contained in this publication. The respective user must check its accuracy by consulting other sources of reference in each individual case. The use of registered names, trademarks etc. in this publication, even if not identified as such, does not imply that they are exempt from the relevant protective laws and regulations or free for general use. This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, re-use of illustrations, recitation, broadcasting, reproduction on microfilms or in other ways, and storage in data banks. For any kind of use, permission of the copyright owner must be obtained. © 2009 Birkhäuser Verlag, P.O. Box 133, CH-4010 Basel, Switzerland Part of Springer Science+Business Media Printed on acid-free paper produced from chlorine-free pulp. TFC d Cover illustration: see p. 198; with friendly permission of Elizabeth Pappas Printed in Germany ISBN 978-3-7643-9894-1 e-ISBN 978-3-7643-9912-2 987654321 www. birkhauser.ch
Contents List of contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
vii
Preface
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ix
Isabel Atzl and Roland Helms A short history of the common cold . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
1
Ronald Eccles Mechanisms of symptoms of common cold and flu
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Alex J. Elliot and Douglas M. Fleming Common respiratory infections diagnosed in general practice
23
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47
Ian M. Mackay, Katherine E. Arden and Stephen B. Lambert Epidemiology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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