Comparing the SF-12 and SF-36 health status questionnaires in patients with and without obesity

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Comparing the SF-12 and SF-36 health status questionnaires in patients with and without obesity Christina C Wee*, Roger B Davis and Mary Beth Hamel Address: Division of General Medicine and Primary Care, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA Email: Christina C Wee* - [email protected]; Roger B Davis - [email protected]; Mary Beth Hamel - [email protected] * Corresponding author

Published: 30 January 2008 Health and Quality of Life Outcomes 2008, 6:11

doi:10.1186/1477-7525-6-11

Received: 22 August 2007 Accepted: 30 January 2008

This article is available from: http://www.hqlo.com/content/6/1/11 © 2008 Wee et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract Objective: To assess how well the SF-36, a well-validated generic quality of life (QOL) instrument, compares with its shorter adaptation, the SF-12, in capturing differences in QOL among patients with and without obesity. Methods: We compared the correlation between the physical (PCS) and mental (MCS) component summary measures of the SF-12 and SF-36 among 356 primary care patients using Pearson coefficients (r) and conducted linear regression models to see how these summary measures captures the variation across BMI. We used model R2 to assess qualitatively how well each measure explained the variation across BMI. Results: Correlations between SF-12 and SF-36 were higher for the PCS in obese (r = 0.89) compared to overweight (r = 0.73) and normal weight patients (r = 0.75), p < 0.001, but were similar for the MCS across BMI. Compared to normal weight patients, obese patients scored 8.8 points lower on the PCS-12 and 5.7 points lower on the PCS-36 after adjustment for age, sex, and race; the model R2 was higher with PCS-12 (R2 = 0.22) than with PCS-36 (R2 = 0.16). BMI was not significantly associated with either the MCS-12 or MCS-36. Conclusion: The SF-12 correlated highly with SF-36 in obese and non-obese patients and appeared to be a better measure of differences in QOL associated with BMI.

Background In addition to its etiologic role in many common medical conditions, obesity has profound adverse physical, social, and economic consequences that can negatively affect quality of life, an increasingly important outcome considered by patients, clinicians, and policymakers alike. As a result, quality of life has become an important endpoint assessed in studies of obesity and weight loss interventions.

One of the most straightforward ways of measuring quality of life (QOL) is through the use of health status measures where patients are asked to rate different aspects of their life. Perhaps the most commonly used measure in QOL research is the Short-Form 36 or SF-36, a generic measure d