Complementary and Alternative Medicine for the Management of Interstitial Cystitis/Bladder Pain Syndrome: a Recent Updat

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BPS/INTERSTITIAL CYSTITIS (D CASTRO-DIAZ AND Y IGAWA, SECTION EDITORS)

Complementary and Alternative Medicine for the Management of Interstitial Cystitis/Bladder Pain Syndrome: a Recent Update Xibei Jia 1 & Tess Crouss 2 & Neha Rana 3 & Kristene E. Whitmore 4,5

# Springer Science+Business Media, LLC, part of Springer Nature 2020

Abstract Purpose of Review Interstitial cystitis and/or bladder pain syndrome (IC/BPS) affect many women in the USA and management of IC/BPS can be challenging for the providers. In addition to conventional treatment options outlined by the American Urologic Association (AUA) guidelines, many complementary and alternative medicines (CAM) have been gaining popularity. Our study aims to review recent publications on CAM and management of IC/BPS. Recent Finding Our literature search included all studies that addressed complementary or alternative methods of treating IC/BPS patients from the last 5 years. We have identified studies that involve the following categories: diet therapy, acupuncture therapy, mind-body intervention, pelvic floor physical therapy, and massage. We have found that intensive dietary manipulation can improve symptoms of IC/BPS, and the effect can last up to a year. Acupuncture therapy can be effective in managing IC/BPS symptoms in the first 3 months after intervention, but the effect decreased over time. Mind-body interventions can be used as an adjunct to the usual care in the treatment of IC/BPS, and it helped improve the Global Response Assessment scores. Lastly, Thiele massage demonstrated negative impact in the perception of pain in patients with IC/BPS and should not be used as a monotherapy. Summary Current studies are limited by small number of patients and mixed quality of evidence. Larger, high-quality studies are needed to evaluate the effect of CAM on IC/BPS symptoms. Other forms of CAM as well as combined therapies should also be studied in the future. Our review concluded that providers should consider CAM as an adjunct in the treatment of IC/BPS. Keywords Complementary and alternative medicine (CAM) . Interstitial cystitis (IC) . Bladder pain syndrome (BPS)

Introduction The American Urologic Association (AUA) and the Society for Urodynamics Female Pelvic Medicine and Urogenital Reconstruction (SUFU) define interstitial cystitis (IC)/Bladder Pain Syndrome (BPS) as “an unpleasant sensation (pain, pressure, discomfort) perceived to be related to the urinary bladder,

associated with lower urinary tract symptoms of more than 6 weeks duration, in the absence of infection or other identifiable causes” [1]. The European Society for the Study of Interstitial Cystitis (ESSIC) uses a similar IC/BPS definition but requires a longer duration of symptoms (more than 6 months) [2]. IC/BPS affects 3.3 to 7.9 million women in the USA of age 18 years or older [3]. The prevalence of IC/BPS increases with

This article is part of the Topical Collection on BPS/Interstitial Cystitis * Kristene E. Whitmore [email protected]

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Department of Obstetrics and Gynecology, Divisi