Computational Fluid Dynamics for Mechanical Circulatory Support Device Development
Computational fluid dynamics (CFD) has become an established tool for mechanical circulatory support device development. At the same time, CFD is used in research efforts to investigate the challenges that mechanical circulatory support still faces today.
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Mechanical Support for Heart Failure
Jamshid H. Karimov Kiyotaka Fukamachi • Randall C. Starling Editors
Mechanical Support for Heart Failure Current Solutions and New Technologies
Editors Jamshid H. Karimov Lerner Research Institute, Cleveland Clinic Cleveland Clinic Lerner College of Medicine of Case Western Reserve University Cleveland Clinic Cleveland, OH USA
Kiyotaka Fukamachi Lerner Research Institute, Cleveland Clinic Cleveland Clinic Lerner College of Medicine of Case Western Reserve University Cleveland Clinic Cleveland, OH USA
Randall C. Starling Kaufman Center for Heart Failure Heart, Thoracic, and Vascular Institute Cleveland Clinic Lerner College of Medicine of Case Western Reserve University Cleveland Clinic Cleveland, OH USA
ISBN 978-3-030-47808-7 ISBN 978-3-030-47809-4 (eBook) https://doi.org/10.1007/978-3-030-47809-4 © Springer Nature Switzerland AG 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
To all the forward thinkers and courageous creators of the past, present and future.
Foreword
More than 50 years have passed since the development and initial clinical testing of temporary mechanical cardiac support systems for blood pumps. The National Heart, Lung and Blood Institute (NHLBI) funded those early, ambitious efforts and clinical trials, with the collaboration of several multidisciplinary groups. Since then, research on the artificial heart was geared toward replacing the diseased organ and securing normal physiological functionality with a heart prosthesis. Many significant efforts toward this end have been pursued in the USA and in leading centers around the world. In 1988, NHLBI funding for the total artificial heart was temporarily suspen
