Computed tomography-guided biopsy for small renal masses before or immediately after tumor ablation: factors affecting d

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ORIGINAL ARTICLE

Computed tomography‑guided biopsy for small renal masses before or immediately after tumor ablation: factors affecting diagnostic yield Masafumi Takafuji1 · Masashi Fujimori1   · Atsuhiro Nakatsuka1 · Hiroshi Kodama1 · Takashi Yamanaka1 · Yuichi Sugino1 · Naritaka Matsushita1 · Hideki Kanda2 · Yoshifumi Hirokawa3 · Hajime Sakuma1 Received: 10 June 2020 / Accepted: 24 September 2020 © Japan Radiological Society 2020

Abstract Purpose  To evaluate the diagnostic yield of percutaneous renal mass biopsy (RMB) before and after ablation. Materials and methods  In total, 333 renal masses in 332 consecutive patients underwent computed tomography (CT)-guided biopsies and were included in this study. All biopsies were performed with 18-gauge core needles with CT fluoroscopic guidance before ablation (n  =  234) or immediately after radiofrequency ablation (RFA) (n  =  40) or cryoablation (CA) (n  =  59). The safety and diagnostic yield of RMB were evaluated. Both univariate and multivariate analyses were used to identify factors affecting diagnostic yield. Results  No major complication occurred. The 281 specimens (84%) were diagnostic. There were 257 renal cell carcinomas (77%), 21 benign masses (6%), and 3 metastases (1%). The remaining 52 specimens (16%) were nondiagnostic. The diagnostic yields before ablation, after RFA, and CA were 91% (212/234), 80% (32/40), and 63% (37/59), respectively. Small masses (P  =  0.050 and 0.006), cystic masses (P