Computer Navigation-Assisted Knee Replacement Demonstrates Improved Outcome Compared with Conventional Knee Replacement

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REVIEW ARTICLE

Computer Navigation‑Assisted Knee Replacement Demonstrates Improved Outcome Compared with Conventional Knee Replacement at Mid‑Term Follow‑up: A Systematic Review and Meta‑analysis Charles Ayekoloye1   · Osondu Nwangwu2 · Temitope Alonge3 Received: 12 February 2020 / Accepted: 29 May 2020 © Indian Orthopaedics Association 2020

Abstract The study is a systematic review and meta-analysis of prospective randomised control studies and prospective cohort studies of mid-term functional outcome of total knee replacement undertaken using imageless computer navigation compared with conventional instrumented total knee replacement. The literature search strategy included a search of the electronic databases, visual scanning of reference lists, hand searching of key journals and conference proceedings, and abstracts, citations, and trial registers. In total, 440 papers were retrieved after removal of duplicates, and with further screening, 11 papers were included in the systematic review and 6 papers were considered appropriate for meta-analysis. Analysis of the data showed evidence of a modest improvement in functional outcome at mid-term follow-up with use of imageless computer navigation assistance compared with conventional instrumented total knee replacement with a total score point estimate of 3.36 confidence interval (CI) (− 0.583, 7.298), objective score point estimate of 1.45 CI (0.11, 2.799), and functional score point estimate of 2.4, CI (− 1.174, 5.977). The predominant risk of bias was from random allocation and attrition. There is evidence of a modest improvement in functional outcome with the use of imageless computer navigation assistance compared with conventional instrumented total knee replacement at mid-term follow-up. Keywords  Total knee replacement · Arthroplasty · Computer navigation · Navigation-assisted knee · Imageless navigation · MeSH terms: arthroplasty · Replacement · Knee · Navigation · Computer

Introduction

Electronic supplementary material  The online version of this article (https​://doi.org/10.1007/s4346​5-020-00161​-z) contains supplementary material, which is available to authorized users. * Charles Ayekoloye [email protected] Osondu Nwangwu [email protected] Temitope Alonge [email protected] 1



Oaklands Hospital Salford, 19 Lancaster Road, Salford M6 8AQ, UK

2



Department of Orthopaedics, Luton and Dunstable Hospital, Bedfordshire, UK

3

University College Hospital, Ibadan, Nigeria



Total knee replacement is a highly successful procedure for the treatment of end-stage knee arthritis. It has achieved this by relieving the debilitating pain associated with this condition and the procedure has resulted in restoring functional independence and quality of life [1, 2]. Total knee replacement as currently performed uses manufacturer provided instrumentation that (co-opts) took cognizance of the anatomy of the patient’s knees [3]. The instrumentation enables reproducible cuts on the bone, thereby ensuring a more accurate prosthetic sizing and (implantatio