Contraceptive Steroids Pharmacology and Safety
One of the United States Food and Drug Administration's most difficult tasks is the assessment of risk-benefit ratios for a broad spectrum of therapeutic and prophylactic drugs. Furthermore, it is now widely recog nized that no drug, chemical or even nat
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REPRODUCTIVE BIOLOGY
Series Editor: Sheldon J. Segal
The Rockefeller Foundation New York, New York
THE ANTIPROGESTIN STEROID RU 486 AND HUMAN FERTILITY CONTROL Edited by Etienne-Emile Baulieu and Sheldon J. Segal CONTRACEPTIVE STEROIDS: Pharmacology and Safety Edited by A. T. Gregoire and Richard P. Blye
GOSSYPOL: A Potential Contraceptive for Men Edited by Sheldon J. Segal IMMUNOLOGICAL APPROACHES TO CONTRACEPTION AND PROMOTION OF FERTILITY Edited by G. P. Talwar
A Continuation Order plan is available for this series. A continuation order will bring delivery of each new volume immediately upon publication. Volumes are billed only upon actual shipment. For further information please contact the publisher.
CONTRACEPTIVE STEROIDS Pharmacology and Safety
Edited by
A. T. Gregoire Food and Drug Administration Rockville. Maryland
and
Richard P. stye National Institutes of Health Bethesda. Maryland
PLENUM PRESS • NEW YORK AND LONDON
Library of Congress Cataloging in Publication Data Contraceptive steroids. (Reproductive biology) Based on the proceedings of the Workshop on Animal Testing Requirements for New Generation Steroidal Contraceptives. which included a meeting of the Fertility and Maternal Health Drug Advisory Committee, held Apr. 27-29, 1983 at the National Institutes of Health and sponsored by the Food and Drug Administration and others. Includes bibliographies and index. I. Contraceptive drugs-Side effects-Congresses. 2. Steroid drugs-Side effects-Congresses. 3. Contraceptive drugs-Toxicology-Congresses. 4. Steroid drugs-Toxicology-Congresses. 5. Pharmacology, Experimental-Congresses. I. Gregoire, A. T. II. Blye, Richard P. Ill. Workshop on Animal Testing Requirements for New Generation Steroidal Contraceptives (1983: National Institutes of Health) IV. United States. Food and Drug Administration. Fertility and Maternal Health Drug Advisory Committee. V. Series. IDNLM: I. Animal Testing Alternatives-congresses. 2. Contraceptives-adverse effects-congresses. 3. Contraceptives-pharmacodynamics-congresses. 4. Steroids-pharmacodynamics-congresses. OV 177 C764 19831 RGI37.4.C66 1986 613.9'432 86-20448 ISBN-13:978+4612-9313-2 e-ISBN-13:978+4613-2241-2 DOI:IO.1007/978+4613-2241-2
Based on the proceedings of a Workshop and Meeting of the Fertility and Maternal Health Drugs Advisory Committee, sponsored by the Food and Drug Administration and the National Institutes of Health in cooperation with the Population Council. the World Health Organization, and the Agency for International Development. held April 27-29, 1983, at the National Institutes of Health, Bethesda, Maryland
© 1986 Plenum Press, New York Softcover reprint of the hardcover 1st edition 1986 A Division of Plenum Publishing Corporation 233 Spring Street. New York, N.Y. 10013 All rights reserved No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical. photocopying, microfilming, recording, or otherwise, without written permission from the Publisher
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